Listeria monocytogenes meningitis in adults. Sixteen consecutive cases 1973-1982.

16 adult patients with Listeria monocytogenes meningitis were reviewed to see whether clinical features or initial laboratory findings could discriminate between these patients and patients with purulent meningitis of other causes. Six patients suffered from known predisposing diseases and 4 were alcoholics. The initial clinical picture was indistinguishable from meningitis of other causes.

Imported canine visceral leishmaniasis in Denmark.

The first case of imported visceral leishmaniasis in the dog in Denmark, and probably in Scandinavia, is described. The dog, a 5-year-old female wire-haired bird dog, became ill about 21 months after it had returned from a year's stay in Spain (Malaga). The clinical signs were fever, lameness, enlargement of the popliteal lymph nodes and weight loss.

Postpartum autoimmune thyroid disorder associated with HLA-DR4?

Thirteen Danish women with postpartum thyroiditis were HLA-A, B, C and -DR typed. Nine of ten unrelated probands were DR4-positive which is significantly (corrected p = .01) different from the frequency (34.

875 cases of bacterial meningitis: diagnostic procedures and the impact of preadmission antibiotic therapy. Part III of a three-part series.

Data on the bacteriological findings, diagnostic measures and clinical course of 875 patients with bacterial meningitis are presented. Findings from the medical records and from a follow-up questionnaire survey of 667 of these cases revealed no significant difference between patients treated with antibiotics before admission (pretreated) and those who were not treated before admission (non-pretreated) with respect to clinical condition on admission, mortality and late sequelae. Pretreatment was, however, associated with a longer duration of symptoms.

Sequelae from bacterial meningitis and their relation to the clinical condition during acute illness, based on 667 questionnaire returns. Part II of a three part series.

During the years 1966-1976, 875 patients with bacterial meningitis were treated at the Department of Infectious Diseases, Rigshospitalet, Denmark. In late 1979 and early 1980 a survey by questionnaire was conducted among survivors concerning the impact of the disease. Replies were received from 667 patients (96.

Eight hundred and seventy-five cases of bacterial meningitis. Part I of a three-part series: clinical data, prognosis, and the role of specialised hospital departments.

Between 1966 and 1976, 875 patients with bacterial meningitis were treated at the Department of Infectious Diseases, Rigshospitalet. Among 495 patients admitted directly to the department, fatality rates were 0.4 per cent for meningococcal infections (including septicaemia), 3.

Epstein-Barr virus in nasopharyngeal and salivary gland carcinomas of Greenland Eskimoes.

Biopsy specimens from nasopharyngeal carcinomas (NPC) or salivary-gland carcinomas (SGC) in Greenland Eskimoes were examined for the presence of Epstein-Barr virus (EBV) DNA and sera from the patients were tested for EBV-specific antibody titres. Six out of 7 NPCs and one from an undifferentiated SGG were positive for EBV DNA. The EBV-specific antibody spectra and titres of the patients with NPC or undifferentiated SGG conformed to the results of earlier studies in other high-incidence areas.

In-use tests of disinfectants.

In two different laboratories three methods were applied for in-use testing of 400 samples of disinfectants, primarily aldehyde and phenolic solutions, collected in 30 wards at 11 Danish hospitals. The results obtained with the Kelsey-Maurer test, the membrane filtration technique, and a standardized challenge test were in complete accordance, however, the challenge test revealed a few more inefficient samples, than the two other methods. For routine use at hospital laboratories the choice between the Kelsey-Maurer test or the modified Kelsey-Maurer technique using membrane filtration may be guided by the available equipment.

Radiation resistance of Candida parapsilosis.

The radiation resistance of 30 strains classified as Candida parapsilosis was examined. The strains originated partly from environments where ionizing radiation was used for research or routine purposes, partly from environments with no known possibility for selection of strains with unusually high radiation resistance. D-6 values between 1.

Radiation-resistant micro-organisms isolated from textiles.

Towels from private homes and public offices and underwear contaminated by being used by employees at a public health laboratory were examined for occurrence of radiation-resistant bacteria and fungi. Three different methods were used for isolation of the most resistant organisms, one with multiplication of the microbial population prior to an irradiation used for selection, and two without this multiplication and with the organisms placed on membrane filters or in situ on the textiles, respectively. A total of 44 different strains were isolated.

Biological indicators for the control of ethylene oxide sterilization.

A new biological indicator has been developed for the control of ethylene oxide sterilization, particularly for large scale sterilization of disposable medical equipment. The aim has been to provide the new indicator with the same resistance to the combined effect of ethylene oxide and water vapour as the biological indicator referred to by the health authorities in Scandinavia. The reference indicator contains spores of a Danish test strain, Bacillus subtilis, in sand.

Osteochondral fracture associated with dislocation of the patella: another mechanism of injury.

An apparently not previously reported type of osteochondral fracture of the lateral femoral condyle associated with dislocation of the patella is presented. The mechanism of the fracture is described as forced inward rotation of the femur against the tibia. Internal fixation is the surgical treatment of choice in this type of fracture.

Artificial hyperventilation during 21 years in three cases of complete respiratory paralysis.

Three patients with paralytic poliomyelitis have been ventilated via tracheostomy with uncuffed silver cannula for 21 years, with high tidal volumes of atmospheric air (8.3, 7.2, and 5.

[Atresia of the ear (author's transl)].

The results of operations for congenital deformities of the external and middle ear throughout a 10-year period, 1962-1972, are presented. 38 ears were operated upon, of which 26 obtained an average hearing gain of 25 dB. In 12 ears no improvement was obtained, and no ear became worse.