Publications by authors named "Kristen Werth"
Article Synopsis
- The Beat AML program analyzed tumor specimens from 562 AML patients to examine complex mutations and drug responses using whole-exome and RNA sequencing.* -
- The study discovered previously undetected mutations and identified how certain drug responses are linked to specific combinations of these mutations.* -
- Findings, including gene expression signatures related to drug responses, are available through the Beat AML data viewer, enabling further research on AML biology.*
Background: Administration of vaccines by needle-free technology such as jet injection might offer an alternative to needles and syringes that avoids the issue of needle phobia and the risk of needle-stick injury. We aimed to assess the immunogenicity and safety of trivalent influenza vaccine given by needle-free jet injector compared with needle and syringe.
Methods: For this randomised, comparator-controlled trial, we randomly assigned (1:1) healthy adults (aged 18-64 years) who attended one of four employee health clinics in the University of Colorado health system, with stratification by site, to receive one dose of the trivalent inactivated influenza vaccine Afluria given either intramuscularly with a needle-free jet injector (Stratis; PharmaJet, Golden, CO, USA) or with needle and syringe.