Publications by authors named "Kristen Torres"

Article Synopsis
  • The study investigates synaptic density in autistic adults using positron emission tomography (PET) and synaptic vesicle glycoprotein 2A (SV2A) as a marker.
  • Results show that autistic individuals exhibit a 17% lower synaptic density across the whole cortex compared to non-autistic peers, with significant deficits in various brain regions, especially the prefrontal cortex.
  • The findings suggest that lower synaptic density is associated with increased autistic features, pointing to a potential molecular basis for autism that requires further exploration.
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Objective: Burnout in healthcare professionals (HCPs) is a pressing issue in healthcare. We report the long-term impact of our previous creative arts therapy (CAT) intervention for reducing psychological distress in HCPs.

Methods: Healthcare professionals were randomized to CAT intervention or control group.

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Background: Centanafadine is an inhibitor of reuptake transporters for norepinephrine (NET), dopamine (DAT) and serotonin (SERT).

Aims: This phase 1, adaptive-design positron emission tomography study investigated the occupancy time course of NET, DAT, and SERT and the relationship to centanafadine plasma concentrations.

Methods: Healthy adult males received centanafadine sustained-release 400 mg/day for 4 days ( = 6) or 800 mg in a single day ( = 4).

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Background: Work-related psychological distress is common among health care professionals. We determined whether 4 creative arts therapy (CAT) programs were acceptable, feasible, and improved psychological distress and job turnover intention in health care professionals with burnout symptoms.

Methods: Health care professionals were enrolled during the coronavirus disease (COVID-19) pandemic from September 2020 until July 2021.

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The positron emission tomography radioligand [C]UCB-J binds to synaptic vesicle glycoprotein 2 A (SV2A), a regulator of vesicle release. Increased neuronal firing could potentially affect tracer concentrations if binding site availability is altered during vesicle exocytosis. This study assessed whether physiological brain activation induces changes in [C]UCB-J tissue influx (), volume of distribution (), or binding potential ().

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: Starting in 2013, the Mental Health Youth Action Board, made up of 15 teens ages 15-18, was created to advise a large children's hospital on improvements in mental health care and produce social action projects to impact community perceptions of mental health.: This participatory qualitative case study explored the experiences of 14 young people who participated in the Mental Health Youth Action Board between 2013 and 2016.: There were two higher order themes: process and outcomes.

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