Publications by authors named "Kristen N Sigfrid"
Purpose: To investigate the molecular basis of inherited retinal dysplasia in miniature Schnauzers.
Methods: Retina and retinal pigment epithelial tissues were collected from canine subjects at the age of 3 weeks. Total RNA isolated from these tissues was reverse transcribed to make representative cDNA pools that were compared for differences in gene expression by using a subtractive hybridization technique referred to as representational difference analysis (RDA).