Publications by authors named "Kristen MacEachern"

Objectives: Across guidelines, protein dosing for critically ill patients with obesity varies considerably. The objective of this analysis was to evaluate whether this population would benefit from higher doses of protein.

Design: A post hoc subgroup analysis of the effect of higher protein dosing in critically ill patients with high nutritional risk (EFFORT Protein): an international, multicenter, pragmatic, registry-based randomized trial.

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Article Synopsis
  • Current nutrition guidelines suggest high-dose protein for critically ill patients, but evidence shows it may not improve outcomes, especially in those with acute kidney injury (AKI).
  • A post hoc analysis of the EFFORT Protein trial examined outcomes for patients with AKI receiving either high or usual protein doses, finding that high protein was linked to slower recovery and higher mortality.
  • The results indicate that high protein intake in critically ill patients with AKI could be harmful, warranting a reevaluation of current high-protein recommendations for these patients.
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Adults with acute leukemia (AL) are at high risk of malnutrition due to their disease and treatment side effects and may be admitted to the intensive care unit (ICU), further increasing the risk of malnutrition. Although ICU care includes some form of nutrition, patients typically receive less than prescribed energy and protein. Our objective was to characterize the nutrition care for critically ill patients with AL.

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Background: Critically ill patients are at increased risk of developing malnutrition-related complications because of physiological changes, suboptimal delivery, and reduced intake. Strategies to improve nutrition during critical illness recovery are required to prevent iatrogenic underfeeding and risk of malnutrition. The purpose of this study was to assess the feasibility and acceptability of a novel family-centered intervention to improve nutrition in critically ill patients.

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