Glucose permeability of human, bovine, and porcine corneas in vitro.

Purpose: To measure glucose flux across human, bovine, and porcine corneas and to determine the diffusion coefficient of each type of cornea.

Methods: Diffusion of glucose across human (n = 8), bovine (n = 7), and pig corneas (n = 8) was measured using a modified blind well chamber apparatus (Boyden chamber). Dialysis membranes (n = 7) and nonporous Mylar membranes (n = 7) were used as positive and negative controls, respectively.