Effects of Omega-3 Polyunsaturated Fatty Acid Supplementation on Bone Turnover in Older Women.

Animal and human studies indicate that omega (n)-3 polyunsaturated fatty acids (PUFA) can influence bone health. We conducted a randomized, double-blind, placebo-controlled trial of the effects of n-3 long chain (LC) PUFA supplementation (N-3 LCPUFA) on red blood cell (RBC) fatty acid levels and bone turnover markers in older postmenopausal women. One hundred and twenty-six postmenopausal women (mean age 75±7 years) were treated with n-3 LCPUFA (1.

Effects of transdermal testosterone on bone and muscle in older men with low bioavailable testosterone levels, low bone mass, and physical frailty.

Objectives: To investigate the effects of testosterone supplementation on bone, body composition, muscle, physical function, and safety in older men.

Design: Double-blind, randomized, placebo-controlled trial.

Setting: A major medical institution.

Osteoporosis risk in frail older adults in assisted living.

Objectives: To compare osteoporosis risk in residents of assisted living (AL) with that of age- and sex-matched community-dwelling adults.

Design: Cross-sectional.

Setting: Community and AL facilities in Connecticut.