A spectroscopic assessment of interaction between 4% articaine hydrochloride with adrenaline and various endodontic irrigants.

Background: Interaction between 2% lidocaine HCl (with and without adrenaline) and sodium hypochlorite (NaOCl) resulted in a toxic precipitate formation. The aim of this study was to assess the interaction between 4% articaine hydrochloride with adrenaline (AHa) and commonly used endodontic irrigants 3% NaOCl, 2% chlorhexidine (CHX), and 17% ethylenediaminetetraacetic acid (EDTA) using spectroscopic analyses.

Materials And Methods: In this study, 3% NaOCl, 2% CHX, and 17% EDTA were mixed with 4% AHa individually.