Investigating antibacterial activity of biosynthesized silver oxide nanoparticles using Phragmanthera Macrosolen L. leaf extract.

The crude leaf extract of Phragmanthera macrosolen L. has been utilized for the first time as an effective reducing, capping and stabilizing agent to synthesize silver oxide nanoparticles (AgO NPs) through a green approach. The prepared AgO NPs were analyzed by scanning electron-microscopy (SEM), High Resolution Transmission electron microscope (HR-TEM), X-ray diffractions (XRD), Fourier transforms infrared (FTIR) spectroscopy, energy dispersive spectroscopy (EDS), and Ultra-violet visible spectrometry (UV-Vis).

Prediction of android ransomware with deep learning model using hybrid cryptography.

In recent times, the number of malware on Android mobile phones has been growing, and a new kind of malware is Android ransomware. This research aims to address the emerging concerns about Android ransomware in the mobile sector. Previous studies highlight that the number of new Android ransomware is increasing annually, which poses a huge threat to the privacy of mobile phone users for sensitive data.

Drug Repositioning Using Computer-aided Drug Design (CADD).

Drug repositioning is a method of using authorized drugs for other unusually complex diseases. Compared to new drug development, this method is fast, low in cost, and effective. Through the use of outstanding bioinformatics tools, such as computer-aided drug design (CADD), computer strategies play a vital role in the re-transformation of drugs.

Shariant platform: Enabling evidence sharing across Australian clinical genetic-testing laboratories to support variant interpretation.

Sharing genomic variant interpretations across laboratories promotes consistency in variant assertions. A landscape analysis of Australian clinical genetic-testing laboratories in 2017 identified that, despite the national-accreditation-body recommendations encouraging laboratories to submit genotypic data to clinical databases, fewer than 300 variants had been shared to the ClinVar public database. Consultations with Australian laboratories identified resource constraints limiting routine application of manual processes, consent issues, and differences in interpretation systems as barriers to sharing.

Energy recovery of waste plastics into diesel fuel with ethanol and ethoxy ethyl acetate additives on circular economy strategy.

The widespread use of plastic goods creates huge disposal issues and environmental concerns. Increasing emphasis has been paid to the notion of a circular economy, which might have a significant impact on the demand for plastic raw materials. Post-consumer plastics recycling is a major focus of the nation's circular economy.

Sustainability and Environmental Impact of Ethanol and Oxyhydrogen Addition on Nanocoated Gasoline Engine.

Climate change, clean air, renewable energy, nontoxic surroundings, and the opportunity to live in a healthy community are just few of the issues that environmental sustainability addresses. To improve environmental health and quality of life, several researchers have turned their attention to alternative energy sources like ethanol and oxyhydrogen. In latest years, significant progress has been made in the development of ethanol and hydrogen as clean energy sources.

Curcumin-Based Inhibitors of Thrombosis and Cancer Metastasis Promoting Factor CLEC 2 from Traditional Medicinal Species .

The CLEC-2 receptor protein belongs to the C-type lectin superfamily of transmembrane receptors that have one or more C-type lectin-like domains. CLEC-2 is a physiological binding receptor of podoplanin (PDPN), which is expressed on specific tumour cell types and involved in tumour cell-induced platelet aggregation and tumour metastasis. CLEC-2 and podoplanin-expressing tumour cells interact to increase angiogenesis, tumour development, and metastasis.

Examining Impacts of Acidic Bath Temperature on Nano-Synthesized Lead Selenide Thin Films for the Application of Solar Cells.

The influence of bath temperature on nano-manufactured PbSe (lead selenide) films was successfully generated by utilizing CBD on the acid solution's metal surface tool. Pb (NO) was employed as a lead ion source as a precursor, while NaOSe was used as a selenide ion source. The XRD characterization revealed that the prepared samples are the property of crystalline structure (111), (101), (100), and (110) Miller indices.

Bond Strength of Acrylic Denture Tooth to a Novel Thermo-Polymerized Denture Base Copolymer Containing Cycloaliphatic Comonomer after Mechanical and Thermal Aging.

Background: There are numerous artificial denture tooth materials available of which acrylic resin teeth were used widely. The resin teeth bond chemically to the denture base resin, and this bonding is affected by numerous intrinsic and extrinsic factors. The type of cross-linker in the denture base monomer is one such factor which has a questionable influence on the bond strength.

Nanomaterials for Remediation of Environmental Pollutants.

Today, environmental contamination is a big concern for both developing and developed countries. The primary sources of contamination of land, water, and air are extensive industrialization and intense agricultural activities. Various traditional methods are available for the treatment of different pollutants in the environment, but all have some limitations.

Recommendations by the ClinGen Rett/Angelman-like expert panel for gene-specific variant interpretation methods.

The genes MECP2, CDKL5, FOXG1, UBE3A, SLC9A6, and TCF4 present unique challenges for current ACMG/AMP variant interpretation guidelines. To address those challenges, the Rett and Angelman-like Disorders Variant Curation Expert Panel (Rett/AS VCEP) drafted gene-specific modifications. A pilot study was conducted to test the clarity and accuracy of using the customized variant interpretation criteria.

Anticancer, Enhanced Antibacterial, and Free Radical Scavenging Potential of Fucoidan- ( Source) Mediated Silver Nanoparticles.

The present research displays the green synthesis of stable silver nanoparticles (AgNPs). The aqueous solution of Fucoidan from source (brown marine algae) is used as a reducing and capping agent. UV-Vis spectroscopy, XRD, FT-IR, SEM, EDX, and TEM with selected area electron diffraction are used to characterize the synthesized silver nanoparticles (AgNPs).

Australia and New Zealand renal gene panel testing in routine clinical practice of 542 families.

Genetic testing in nephrology clinical practice has moved rapidly from a rare specialized test to routine practice both in pediatric and adult nephrology. However, clear information pertaining to the likely outcome of testing is still missing. Here we describe the experience of the accredited Australia and New Zealand Renal Gene Panels clinical service, reporting on sequencing for 552 individuals from 542 families with suspected kidney disease in Australia and New Zealand.

Genome-wide transcriptomic and proteomic studies of Rett syndrome mouse models identify common signaling pathways and cellular functions as potential therapeutic targets.

The discovery that Rett syndrome is caused by mutations in the MECP2 gene has provided a major breakthrough in our understanding of the disorder. However, despite this, there is still limited understanding of the underlying pathophysiology of the disorder hampering the development of curative treatments. Over the years, a number of animal models have been developed contributing to our knowledge of the role of MECP2 in development and improving our understanding of how subtle expression levels affect brain morphology and function.

Comparison of Rate of Canine Retraction and Anchorage Potential between Mini-implant and Conventional Molar Anchorage: An Study.

Aim: The aim of this study was to compare the rate of canine retraction, the anchorage loss, and the change in the inclination of the first molars between molar and mini-implant anchorage.

Objective: (1) To compare the rate of canine retraction between conventional molar anchorage and mini-implant anchorage in the maxilla and mandible. (2) To compare the amount of anchor loss between mini-implant-anchored and molar-anchored sides during canine retraction in the maxilla and mandible.

Comparison of surface roughness of enamel and shear bond strength, between conventional acid etching and erbium, chromium-doped: Yttrium scandium-gallium-garnet laser etching - An study.

Background: The purpose of the study was to evaluate and to compare the shear bond strength (SBS), adhesive remnant index, and surface roughness of the samples bonded after etching with phosphoric acid and erbium, chromium-doped: Yttrium scandium-gallium-garnet (Er, Cr: YSGG) laser.

Materials And Methods: In the present analytical/descriptive study, 90 premolars extracted for orthodontic purposes were used, out of which 75 were randomly divided into five groups where five different methods were used to prepare the enamel for bonding; etching with 37% phosphoric acid for 15 s, irradiation with Er, Cr: YSGG laser at 1 watt for 10 s and 20 s, and irradiation with Er, Cr: YSGG laser at 1.5 watt for 10 s and 20 s.

Assessment of Regeneration of Bone in the Extracted Third Molar Sockets Augmented Using Xenograft (CollaPlug Zimmer) in Comparison with the Normal Healing on the Contralateral Side.

Introduction: Alveolar bone resorption is a significant clinical problem. Bone loss in third molar region following extraction or surgical removal not only leads to periodontal problems in second molar region but also it may lead to some serious problems like increased incidence of angle fractures. In order to reduce the risks following third molar surgery, the socket should be augmented with bone grafts.

Does Change in Thread Shape Influence the Pull Out Strength of Mini Implants? An In vitro Study.

Introduction: Mini implants form a valuable source for absolute anchorage thereby helping in achieving ideal treatment outcome. Stability of the mini implant is one of the important factors affecting the success of mini implants. Thread shape is a critical factor in the engineering design of mini implant, which affects the primary stability.

RettBASE: Rett syndrome database update.

Rett syndrome (RTT) is an X-linked progressive neurodevelopmental disorder that primarily affects females. Mutations in the MECP2 gene have been attributed as the major genetic cause of RTT. Recently, mutations in CDKL5 and FOXG1 genes have also been suggested to give rise to RTT, although subsequent more extensive studies suggest that diseases resulting from mutations in these two genes should be considered as distinct clinical entities.

Implant-based overdenture: A review in patient perspective.

A review in affected person's attitude in abstract care of edentulous patients has to be a priority in elderly individuals. The development of complete dentures (CDs) has been the selection of remedy retaining in mind the socioeconomic popularity, age, and nutritional elements. However, most of the patients complain of loss of retention in mandibular implant-supported overdentures (ODs), which compensated the downside of the loss of retention in complete dentures (CDs).

Adjunctive aids for the detection of oral premalignancy.

Early detection of cancer greatly decreases the morbidity and mortality rates and thereby increases the 5-year survival rates. In developing countries like India where the disease is highly prevalent focus is mainly on decreasing the mortality rates which can be easily achieved by detection at an asymptomatic stage. Visual examination has been the standard screening method for screening oral cancer through several decades, and it is well known that conventional visual examination is limited to subjective interpretation and cannot be easily achieved in certain anatomical sites.