Clinical Experience of Use of High-dose Intravenous Methylprednisolone in Children With Acute Moderate to Severe Colitis.

Objectives: Treatment of acute severe colitis (ASC) has been associated with high morbidity and high colectomy rate in children. In the prebiologics era, our centre used short-term high-dose intravenous corticosteroids (IVCS) at 2 to 30 mg · kg · day. We conducted a retrospective review to compare efficacy of different dosing regimes of IVCS.

A new method in the diagnosis of reflux esophagitis: confocal laser endomicroscopy.

Background: The diagnosis of GERD is made by using a combination of clinical symptoms, pH study, endoscopy, and histology. Histologic changes include basal cell hyperplasia and papillary elongation. Confocal laser endomicroscopy (CLE) enables surface and subsurface imaging of living cells in vivo at ×1000 magnification and up to 250 μm below the tissue surface.

Role of confocal endomicroscopy in the diagnosis of celiac disease.

Background And Aims: Confocal laser endomicroscopy (CLE) is a recent development that enables surface and subsurface imaging of living cells in vivo at 1000 x magnification. The aims of the present study were to define confocal features of celiac disease (CD) and to evaluate the usefulness of the CLE in the diagnosis of CD in children in comparison to histology.

Patients And Methods: Nine patients (8 girls) with a median age of 8.

Double balloon enteroscopy in children: diagnosis, treatment, and safety.

Aim: To assess the feasibility and utility of double balloon enteroscopy (DBE) in the management of small bowel diseases in children.

Methods: Fourteen patients (10 males) with a median age of 12.9 years (range 8.

Feasibility of confocal endomicroscopy in the diagnosis of pediatric gastrointestinal disorders.

Aim: To evaluate the feasibility and utility of confocal laser endomicroscopy (CLE) in the description of normal gastrointestinal (GI) mucosa and in the diagnosis of GI disorders in children, in comparison to histology.

Methods: Forty-four patients (19 female) median age 10.9 years (range 0.