Establishing the reliability of incisive papilla and palatal rugae patterns in individual identification.

Context: The study of palatal rugae forms an important basis of human identification, especially due to mass disasters where routinely used techniques may not be helpful.

Aims: This study aimed at evaluating the palatal rugae and incisive papilla on the basis of shape.

Settings And Design: The study was conducted in 280 individuals (males and females) among dental students of Dayananda Sagar College of Dental Sciences.

Role of Cathepsin B as a Marker of Malignant Transformation in Oral Lichen Planus: An Immunohistochemical Study.

Introduction: Malignant transformation of Oral Lichen Planus (OLP) remains a much discussed but very less understood realm. Various hypotheses and theories have been put forward to explain the same. Malignant transformation is a complex interplay of epithelial mesenchymal factors acting in tandem.

Immunohistochemical Expression of Cathepsin D in Primary and Recurrent Squamous Cell Carcinoma.

Aim: The aim of this study is to analyze and compare the immunohistochemical expression of cathepsin B in primary oral squamous cell carcinoma (OSCC) and recurrent OSCC.

Materials And Methods: A total of 50 cases were studied immunohistochemically for rabbit polyclonal antihuman cathepsin D expression. A total of 10 cases of breast carcinoma were taken as positive controls.

Evaluation of transforming growth factor beta1 gene in oral submucous fibrosis induced in Sprague-Dawley rats by injections of areca nut and pan masala (commercial areca nut product) extracts.

Context: Oral submucous fibrosis (OSF) is a potentially malignant oral disorder causally linked to the habit of chewing arecanut. The pathogenesis of the disorder is multifactorial and transforming growth factor beta (TGF-beta) is a prominent player in the induction of fibrosis. The alkaloids of the arecanut seem to target the TGF-beta and the deposition of collagen is predominantly mediated through this cytokine.

Sexual dimorphism in tooth morphometrics: An evaluation of the parameters.

Aims And Objectives: Sexual dimorphism refers to the variations in tooth size and shape between the sexes. The consistency of these variations is valuable in the identification of the sex of an individual in times of mass disaster when whole body parts get destroyed or are unavailable. There exist differences in the expression of these variables across races and regions.

Transforming growth factor-β1 and TGF-β2 act synergistically in the fibrotic pathway in oral submucous fibrosis: An immunohistochemical observation.

Background And Objectives: Oral Submucous Fibrosis (OSF) is a potentially malignant oral disorder which leads to fibrosis of the oral mucosa and has a high rate of malignant transformation. The consumption of various forms of areca nut is causatively linked to the condition. The constituents of areca nut activate several pro-fibrotic cytokines, chiefly transforming growth factor-β1, β2, which leads to an increased deposition and decreased degradation of extracellular matrix and collagen.

Amelogenin in odontogenic cysts and tumors: An immunohistochemical study.

Background: Amelogenins are the major enamel proteins that play a major role in the biomineralization and structural organization of enamel. Aberrations of enamel-related proteins are thought to be involved in oncogenesis of odontogenic epithelium. The expression of amelogenin is possibly an indicator of differentiation of epithelial cells in the odontogenic lesions.

Spindle cell variant of ameloblastic carcinoma arising from an unicystic amelobastoma: Report of a rare case.

Malignant transformation of ameloblastomas arising from an odontogenic cyst or de novo is well-recognized. Malignancies in ameloblastomas may involve metastasis or a local dysplastic change in the tissue. The latter are classified as ameloblastic carcinomas.