Seed bacterization with siderophore-producing bacteria: a strategy to enhance growth and alkaloid content in Catharanthus roseus.

Catharanthus roseus is a medicinal plant widely known for producing monoterpenoid indole alkaloids (MIAs), including therapeutic compounds such as vinblastine and vincristine, which are crucial for cancer treatment. However, the naturally low concentration of these alkaloids in plant tissues poses a significant challenge for large-scale production. This study explores the application of siderophore-producing bacteria for seed bacterization of Catharanthus roseus to enhance the production of MIAs, including vindoline, catharanthine, and vinblastine.

Agricultural Wastes to Value-Added Products: Economic and Environmental Perspectives for Waste Conversion.

The conversion of agricultural wastes to value-added products has emerged as a pivotal strategy in fostering economic transformation. This chapter explores the transformative potential of converting agricultural residues into valued commodities that contribute to sustainability and economic growth. Agricultural wastes, often considered environmental liabilities, possess untapped benefits with great economic value.

sp. nov., isolated from cow milk cheese in Nigeria.

During microbial assessment of cow milk cheese products in the city of Ilorin, Nigeria, a -like isolate was detected that could not be assigned to any known species. Whole-genome sequence analyses against all currently known 26 species confirmed that this isolate constitutes a new taxon within the genus , with highest similarity to (average nucleotide identity blast of 82.66%, DNA-DNA hybridization of 28.

Effect of co-administration of metformin and extracts of D.Don leaves on alloxan-induced diabetes in rats.

Background And Aim: The present study evaluates the antidiabetic effects of aqueous (CPAQ) and methanolic (CPME) extract of D. Don singly and/or in combination with metformin in alloxan-induced diabetic rats.

Experimental Procedure: CPAQ and CPME (400 mg/kg dose), metformin (120 mg/kg) and two different combinations of plant extracts and metformin (200 + 60 mg/kg and 400 mg/kg + 60 mg/kg) were orally given to alloxan-induced diabetic rats for 21 days.

Molecular modelling studies and identification of novel phytochemical inhibitor of DLL3.

Prostate cancer has been recently considered the most diagnosed cancer in male. DLL3 is overexpressed in CRPC-NE but not in localised prostate cancer or BPH. There are no effective treatments for neuroendocrine differentiated prostate cancer due to a lack of understanding of DLL3 structure and function.

Isolation and characterization of from the fish gut for fermentation with carbohydrates from agro-industrial waste.

This study focused on agro-industrial waste such as fruit peels by extracting prebiotics as a carbon source for lactic acid bacteria (LAB). Four strains of LAB were selected from (B2 and B3) and (R4 and R5), and identified as through 16S rRNA gene sequencing. The analysis of probiotic characteristics revealed that all four strains were able to tolerate sodium chloride (up to 7 %), bile salt (up to 3 %), and broad range of pH (2-9).

Molecular identification and biocontrol activity of sugarcane rhizosphere bacteria against red rot pathogen .

A total of 226 sugarcane rhizosphere-associated bacterial strains from the six different cultivars were screened against three pathogenic strains of (cfNAV, cfCHA, and cf8436) for the suppression of red rot disease. On the basis of mycelial growth inhibition in dual culture assay, 26 bacteria were selected for further characterization of morphology, biochemical activity, plant-growth-promoting (PGP) activity, antifungal potential and molecular identity by 16S rRNA gene sequence. On the basis of the 16S rRNA gene sequencing, it was found that the isolates belonged to proteobacteria (13), Firmicutes (10), and Bacteroides (3).