In the present work, we propose an experimental setup to investigate the effect of atmospheric turbulence on user-defined beams. The user-defined beams were formed by writing reconfigurable patterns on a spatial light modulator, allowing the impact of atmospheric turbulence to be investigated simultaneously and in real time. The programmable controllability provides several flexibilities to the system, such as the ability to create different beam types simultaneously, control the separation between different beams, compensate for aberrations, and easily switch between different beam types.
View Article and Find Full Text PDFA 42-year-old chronic alcoholic, nondrug addict male patient with a normal sexual and marital history was brought by relatives to the emergency department of Government Medical College, Kota. He had gradually increasing yellow discoloration of eyes and body for 7 days, progressively worsening altered sensorium for 4 days, up to the extent of not being able to recognize family members for the last 2 days. There was no history of any drug intake.
View Article and Find Full Text PDFThis study addresses the challenges of human-robot interactions in real-time environments with adaptive field-programmable gate array (FPGA)-based accelerators. Predicting human posture in indoor environments in confined areas is a significant challenge for service robots. The proposed approach works on two levels: the estimation of human location and the robot's intention to serve based on the human's location at static and adaptive positions.
View Article and Find Full Text PDFDyads can be challenging to recruit for research studies, but detailed reporting on strategies employed to recruit adult-adolescent dyads is rare. We describe experiences recruiting adult-youth dyads for a hypertension education intervention comparing recruitment in an emergency department (ED) setting with a school-based community setting. We found more success in recruiting dyads through a school-based model that started with adolescent youth (19 dyads in 7 weeks with < 1 hour recruitment) compared to an ED-based model that started with adults (2 dyads in 17 weeks with 350 hours of recruitment).
View Article and Find Full Text PDFBackground: Developmental trajectories are crucial for evidence-based prognostication, planning interventions, and monitoring progress in children with cerebral palsy (CP).
Aims: To describe gross motor development patterns of children with CP in rural South India for the five Gross Motor Function Classification System (GMFCS) levels.
Methods: Longitudinal cohort study of 302 children (176 males, 126 females) with CP aged 0 to 10 years, followed by a community-based early intervention program.
Purpose: To document how acute cerebrovascular accidents (CVAs) present first to an ophthalmologist.
Methods: Retrospective, observational, unicentric hospital-based study. The electronic medical records of new patients who presented to the Neuro-ophthalmology department of a tertiary eye hospital in the month of August 2022 were reviewed.
This paper proposes the design of a metasurface for polarization and incident angle-insensitive RCS reduction applications. An ellipse-shaped unit cell is utilized as a polarization converter, which is then arranged to form a checkerboard surface. While a single layer checkerboard structure gives a wideband RCS reduction, a double layer structure yields polarization and incident angle independent operation.
View Article and Find Full Text PDFObjective: The empirical evidence explicitly demonstrates that meditation practice enhances both brain functions and mental well-being. A meditative relaxation approach called the mind sound resonance technique (MSRT) has shown promising effects on children, adolescents, and people with psychological illnesses. This study aimed to investigate the effects of MSRT practice on brain hemodynamics, heart rate variability (HRV), mindfulness, and anxiety levels in college students.
View Article and Find Full Text PDFRationale Of The Trial: Although the use of engineered T cells in cancer immunotherapy has greatly advanced the treatment of hematological malignancies, reaching meaningful clinical responses in the treatment of solid tumors is still challenging. We investigated the safety and tolerability of IMA202 in a first-in-human, dose escalation basket trial in human leucocyte antigen A*02:01 positive patients with melanoma-associated antigen A1 (MAGEA1)-positive advanced solid tumors.
Trial Design: The 2+2 trial design was an algorithmic design based on a maximally acceptable dose-limiting toxicity (DLT) rate of 25% and the sample size was driven by the algorithmic design with a maximum of 16 patients.
Hydrogels are becoming increasingly significant in tissue engineering because of their numerous benefits, including biocompatibility, biodegradability, and their ability to provide a supportive structure for cell proliferation. This study presents the synthesis and characterization of a new multimaterial hydrogel with 3D-printing capabilities composed of copper nanoparticle-reinforced gelatin, polyvinyl alcohol (PVA), and guar gum-based biomaterials intended for tissue engineering applications. Combining CuNPs aims to enhance the hydrogel's antibacterial properties, mechanical strength, and bioactivity, which are essential for successful tissue regeneration.
View Article and Find Full Text PDFIntroduction: Keloid represents a pathological form of scarring. They are very common in the anterior chest area; nearly 50% of all keloids occur in this location. One of the reasons for this is that folliculitis and acne, known for triggering the development of keloids, are common on the anterior chest.
View Article and Find Full Text PDFDisabil Rehabil Assist Technol
January 2025
A paediatric Assistive Technology (AT) Provision Program was implemented by a non-governmental rehabilitation facility in rural South India to support rehabilitation providers in providing needed AT access for children with disabilities. Capacity-building measures for providers and other supports based on the AT needs, barriers, and facilitators to AT access were implemented that aligned with the AT global report for low-middle income countries (LMIC). This study explores how the initiatives from the AT Provision Program have influenced the perspectives of rehabilitation providers on AT access.
View Article and Find Full Text PDFBackground: A disability service organization piloted a parent capacity-building intervention for parents of children with developmental disabilities in rural South India.
Aims: To examine the impact of this parent capacity-building group intervention on parent empowerment, peer support, social inclusion, advocacy skills, and the factors influencing these outcomes.
Methods And Procedures: A qualitative study recruited 37 participants from 17 parent groups through convenience sampling.
Dev Med Child Neurol
December 2024
Aim: To investigate the social capital of families with children with neurodevelopmental disabilities in South India receiving a community-based early intervention (Enabling Inclusion®) program and to explore determinants and associations between social capital and program duration, socio-demographic factors, family empowerment, and caregiver burden.
Method: Using purposive sampling in a cross-sectional study design, 217 families (n = 71 received short Enabling Inclusion [<5 months]; n = 146 received long Enabling Inclusion [>9 months]) were recruited and completed the Short Adapted Social Capital Tool (SASCAT: cognitive, structural), measures of family empowerment, and caregiver strain. Descriptive statistics, regression, and correlations were used for analyses.
Type 2 diabetes patients are more likely to experience cognitive decline (1.5%) and dementia (1.6%) than healthy individuals.
View Article and Find Full Text PDFDespite advances in the management of type 2 diabetes mellitus (T2DM), one-third of patients with diabetes do not achieve the desired glycemic goal. Considering this inadequacy, many agents that activate glucokinase have been investigated over the last two decades but were withdrawn before submission for marketing permission. Dorzagliatin is the first glucokinase activator that has been granted approval for T2DM, only in China.
View Article and Find Full Text PDFObjective: Access to assistive products (APs) is essential to maximising function, participation, and inclusion of persons with disabilities. Challenges to AP access in low- and middle-income countries include stigma, costs, supply, and rehabilitation capacity gaps. This study aimed to examine AT access in the context of a low-resource setting in rural South India.
View Article and Find Full Text PDFBackground and purpose Cerebral haemodynamics and cognitive performance may be adversely affected in type 2 diabetes mellitus (T2DM). Previous studies reported reduced cerebral blood flow (CBF) and altered cerebrovascular reactivity (CVR) in T2DM. Yoga, an ancient holistic health approach, is known to be beneficial for T2DM.
View Article and Find Full Text PDFBackground: Heart-brain synchronization is the integration of mind, body, and spirit. It occurs when the electrical activity of the heart and brain is synchronized. In recent years, there has been mounting curiosity to investigate the effects of meditation on heart-brain synchronization with respect to mental and emotional health and well-being.
View Article and Find Full Text PDFIntroduction: Children with disabilities in low- and middle-income countries face many challenges and lack adequate services, including access to rehabilitation professionals. To address this lack of access, Amar Seva Sangam Ayikudy (ASSA), a non-governmental organization (NGO) in India, designed a technology-leveraged rehabilitation program called Enabling Inclusion (EI), and implemented it in one state (Tamil Nadu, India) before scaling it. The model is supported by the EI app, which enables organizations to screen, assess and monitor progress of children with disabilities via rehabilitation specialists and community rehabilitation workers, and to provide family-centered, goal-based interventions.
View Article and Find Full Text PDFIsolated cases of subacute thyroiditis exist in the early period of COVID-19 vaccination, largely after mRNA vaccines. Here we report late onset thyroid disturbances and persistent health issues in patients of thyroid disorders after COVID-19 vaccination. Seventy-five patients with post COVID-19 vaccination thyroid disturbances were identified.
View Article and Find Full Text PDFOAuth2.0 is a Single Sign-On approach that helps to authorize users to log into multiple applications without re-entering the credentials. Here, the OAuth service provider controls the central repository where data is stored, which may lead to third-party fraud and identity theft.
View Article and Find Full Text PDFAlthough mitochondrial DNA respiration circuit abnormalities are among the most common metabolic diseases to manifest in children, identification can be difficult due to their medical variability. Given the multisystem nature of the condition and its diverse and generalized manifestations, making a final diagnosis often takes a long time. Within this summary, they give an in-depth account of the physical signs of adolescent Mitochondrial Respiratory Chain Disorders (MRCDs),analyze the available diagnostics and treatment possibilities, and emphasize current developments in this field of study.
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