Publications by authors named "Krishna Bihari Gupta"
Management of interstitial lung diseases: A consensus statement of the Indian Chest Society (ICS) and National College of Chest Physicians (NCCP).
Lung India
January 2020
Article Synopsis
- Interstitial lung disease (ILD) is a diverse group of lung disorders, and updated clinical practice guidelines (CPG) are needed for managing ILD beyond idiopathic pulmonary fibrosis (IPF).
- A multidisciplinary group of experts conducted a systematic review of existing literature to create consensus statements based on clinically relevant questions and a modified GRADE approach to evaluate the evidence.
- The resulting guidelines highlight the limitations of available evidence, which was generally of low quality, but aim to assist clinicians in understanding and managing various types of interstitial pneumonias effectively.
The understanding of the pathobiology of Chronic Obstructive Pulmonary Disease (COPD) has undergone a major change in the past three decades. The classical 'protease-antiprotease' hypothesis still holds true, nevertheless, the sequence of the biochemical events which lead to the protease/antiprotease imbalance have been unraveled. For instance, tobacco smoke, a primary risk factor for COPD, contains a plethora of reactive Oxygen/Nitrogen Species (ROS/RNS) that serve to initiate the oxidant/antioxidant imbalance in the respiratory tract of chronic smokers, a phenomenon that is amplified if certain other risk factors co-exist (e.
View Article and Find Full Text PDFMalnutrition and tuberculosis are both problems of considerable magnitude in most of the underdeveloped regions of the world. These two problems tend to interact with each other. Tuberculosis mortality rates in different economic groups in a community tend to vary inversely with their economic levels.
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