A prospective evaluation of helical tomotherapy.

Purpose: To report results from two clinical trials evaluating helical tomotherapy (HT).

Methods And Materials: Patients were enrolled in one of two prospective trials of HT (one for palliative and one for radical treatment). Both an HT plan and a companion three-dimensional conformal radiotherapy (3D-CRT) plan were generated.

Intensity-modulated arc therapy for treatment of high-risk endometrial malignancies.

Purpose: We developed an intensity-modulated arc therapy (IMAT) technique for the treatment of women with high-risk endometrial malignancies. In the context of multimodality therapy, nodal and tumor bed irradiation was delivered while respecting tolerance doses for critical structures.

Methods And Materials: Five patients were planned and treated with the IMAT technique after hysterectomy.

Planning evaluation of radiotherapy for complex lung cancer cases using helical tomotherapy.

Lung cancer treatment is one of the most challenging fields in radiotherapy. The aim of the present study was to investigate what role helical tomotherapy (HT), a novel approach to the delivery of highly conformal dose distributions using intensity-modulated radiation fan beams, can play in difficult cases with large target volumes typical for many of these patients. Tomotherapy plans were developed for 15 patients with stage III inoperable non-small-cell lung cancer.