Background And Objectives: Vaccination being the only way to reduce mortality from the dreaded COVID-19 disease, the vaccine was introduced in India as per the advice of the National Expert Group on January 16, 2021. Duration of immune response elicited by the vaccines has always been a matter of content. With new variants emerging every other day, the study was done to look for the antibody response in vaccine recipients post second dose of vaccination.
View Article and Find Full Text PDFPurpose Of The Study: Reversible proximal tubular dysfunction associated with distal renal tubular acidosis (dRTA) mimics type 3 RTA, a condition classically associated with features of both proximal RTA (pRTA) and dRTA. Proximal tubulopathy has been reported in children with primary dRTA, but the data in adults are lacking.
Study Design: In this hospital record-based retrospective study, data from 66 consecutive cases of RTA, between January 2016 to December 2018, were retrieved and analyzed.
Background: Artemisinin and partner-drug resistance in Plasmodium falciparum are major threats to malaria control and elimination. Triple artemisinin-based combination therapies (TACTs), which combine existing co-formulated ACTs with a second partner drug that is slowly eliminated, might provide effective treatment and delay emergence of antimalarial drug resistance.
Methods: In this multicentre, open-label, randomised trial, we recruited patients with uncomplicated P falciparum malaria at 18 hospitals and health clinics in eight countries.
Background: Viper snake bite is a threat to the Indian health system with 83 000 deaths annually. There is a paucity of literature regarding independent risk factors for renal damage due to viper bite. We present the scenario in a rural part of West Bengal and highlight some vital factors to prevent the complications.
View Article and Find Full Text PDFBackground: The liver is the principal site for formation and clearance of lipoproteins. Here we decided to conduct this study to assess the degree of alteration of serum lipid levels in alcoholic liver disease, to compare the different parameters and to find out if there is any correlation between extent of lipid profile changes and severity of chronic liver disease.
Methods: In this comparative, analytical, cross sectional, institution-based, single centre study, the different parameters of fasting lipid profile were compared among 150 randomly selected subjects - 50 each of alcoholic cirrhosis, non-alcoholic cirrhosis and healthy normal - from the OPD and Indoor Wards of department of General Medicine of Midnapore Medical College and Hospital situated in Paschim Medinipur district of West Bengal after taking their written and informed consent within a period from July 2015 to June 2016.
Objective: Snake envenomation is a major cause of death and disability in the developing countries. In India and neighboring countries, the four venomous snakes of concern include - Indian cobra(, Common Krait (); Russell's Viper (); Saw Scaled Viper (). We describe the management protocol for snakebite treatment in a tertiary care hospital of district, West Bengal based on case reports of subjects admitted and treated in Ghatal Subdivisional Hospital(GSH) during 2013-2016.
View Article and Find Full Text PDFObjective: Snakebite is one of the neglected tropical diseases that World Health Organization (WHO) aimed to eradicate. The objective of the study is to investigate the mortality and morbidity due to snakebite at Midnapore Medical College & Hospital in district, West Bengal, India.
Methods & Materials: This is a record-based, retrospective, descriptive epidemiological study conducted from January 2012 to December 2016 at Midnapore Medical College and Hospital(MMCH), district, West Bengal.
Objective: Snakebite is a serious medical problem in district, West Bengal, India. In the present study, hospital based data on snakebite cases and deaths were collected from 10 blocks of the district to obtain a picture of this neglected public health issue.
Methods: Retrospective data of snakebite and deaths from 2012 to 2016 was collected from the 5 Rural hospitals (RH) and 5 Block level Primary Health Centres(BPHC) of the ten blocks of district in a prescribed format addressing issues including the demographic factors regarding the victims, seasonal pattern, history of snakebite in previous 5 years, outcome of the bite, any reporting of death.
A 52-year-old man presented with high-grade fever, headache and painful vesicular skin rash involving the upper trunk and upper extremities, 8 days after initiation of chemotherapy with azathioprine (50 mg/day), which had been prescribed for acral vitiligo. There was neither any history of preceding respiratory or gastrointestinal tract infection, nor was the patient known to have malignancy, drug hypersensitivity, inflammatory bowel disease, vasculitis or other autoimmune disease. Laboratory results revealed leucocytosis with neutrophilia and markedly elevated acute phase reactants.
View Article and Find Full Text PDFPlasmodium infection (mainly p. falciparum) is usually complicated by cerebral malaria, haemolysis, acute kidney injury and respiratory distress. Myocardial involvement is a rare complication of plasmodium infection.
View Article and Find Full Text PDFPost-traumatic seizure (PTS) is the development of recurrent seizures following head trauma and has a high clinical relevance. We tried to understand the epidemiology of PTS in a multicentric pro- spective study during the period May 2010 to April 2012. We included 320 patients excluding poor Glasgow coma scale (GCS) ie, <4 and history of previous epilepsy.
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