Lacrimal cutaneous fistula is an uncommon yet clinically significant condition leading to persistent epiphora, recurrent infections, and significant patient discomfort. It can be congenital or acquired. Timely identification and appropriate surgical management are crucial to alleviate symptoms and restore normal lacrimal system functionality.
View Article and Find Full Text PDFCancer cells rely on the tumor microenvironment (TME), a composite of non-malignant cells, and extracellular matrix (ECM), for survival, growth, and metastasis. The ECM contributes to the biomechanical properties of the surrounding tissue, in addition to providing signals for tissue development. Cancer-associated fibroblasts (CAFs) are stromal cells in the TME that are integral to cancer progression.
View Article and Find Full Text PDFBackground: The retina is an uncommon site for metastases, in particular from solid tumors. Some authors have reported a recent increase in the incidence of metastases in infrequent sites, such as brain or bone, probably due to the expanded treatment options and the resulting improved survival. Choroidal metastasis is the most common type of intraocular malignancy.
View Article and Find Full Text PDFOur study aimed to determine the clinical, therapeutic and prognostic features of ocular involvement in patients with Behçet's disease treated in our Department of ophthalmology. We conducted a retrospective data collection from medical records of 20 patients treated at the military hospital in Laayoune. All patients underwent complete ophthalmological examination and fluorescein angiography if necessary.
View Article and Find Full Text PDFBackground: Scleritis is a painful inflammatory process centered in the sclera that may involve the cornea and the underlying uvea. The etiology is commonly idiopathic or autoimmune but some cases are associated with systemic infection such as tuberculosis.
Case Presentation: In this report, we describe an unusual case of a female Moroccan patient who had a long history of bilateral recurrent scleritis associated with peripheral keratopathy and anterior uveitis.
Bull Soc Belge Ophtalmol
July 2014
The pilomatricoma or epithelioma of Malherbe is a mummified benign and rare skin tumor. We report a rare case of palpebral pilomatricoma simulating a chalazion in a 26-year-old patient. This skin tumor is exceptional in adults.
View Article and Find Full Text PDFJ Fr Ophtalmol
January 2013
The observation in a certain number of subjects of an atypical iris depigmentation led us to study this phenomenon. Therefore, the authors engaged in a prospective study of 398 subjects (100 cases in the city of Marrakesh, and 298 in the city of Dakhla). The geography, clinical signs and environmental factors were studied.
View Article and Find Full Text PDFBull Soc Belge Ophtalmol
February 2012
Endogenous panophthalmitis is a rare eye disease with purulent necrosis of all the ocular structures. It is a rare but serious condition that occurs when bacteria cross the blood-ocular barrier and multiply within the eye. Although rare, endogenous panophthamitis is a potentially devastating intraocular infection resulting in a poor visual and anatomic prognosis.
View Article and Find Full Text PDFSarcoidosis is a systemic expression of granuloma found in young adults, but which remains rare in children. Its incidence is underestimated because of the asymptomatic forms. Ocular involvement is present in 25% of the cases.
View Article and Find Full Text PDFBull Soc Belge Ophtalmol
March 2011
Sneddon's syndrome is a particular and rare entity that mostly affects young women and whose diagnosis is based on the coexistence of a cuteaneous livedo and a cerebrovascular ischemic attack. It had be considered as being an expression of an occlusive vasculitis or of antiphospholipid antibody syndrome. We report the case of a 20-year-old female, who had developed a left homonymous hemianopia after ischemic encephalopathy.
View Article and Find Full Text PDFHydrocystoma is a benign tumor whose development involves the sudoriferous eccrine or apocrine glands. We report the case of a giant apocrine hydrocystoma in a 70-year-old female diabetic patient. The tumor's natural progression over 10 years and its volume caused significant functional and aesthetic damage.
View Article and Find Full Text PDFJ Fr Ophtalmol
October 2010
Retinal macrovessel is a rare disease. Since the first description in 1869 by Mauthner, fewer than 30 cases have been reported. We report a case of congenital retinal macrovessel in a 28-year-old patient with no pathological history.
View Article and Find Full Text PDFIntroduction: Tuberculosis is an endemic disease responsible for death and morbidity in developing countries.
Observation: A 50-year-old man with no medical history was admitted to the emergency department for meningism associated with fever and confusion. The ophthalmic exam showed a decline in left visual acuity, reduced to light perception, VIth nerve left oculomotor paralysis, ocular fundus demonstrating a yellow tumor located on the posterior segment, measuring 1.
Angioid streaks are rare lesions of the fundus. They correspond to cracks in the Bruch membrane, which risk choroid neovessel emergence over time. We present the case of a 52-year-old diabetic patient who consulted for a macular syndrome of the left eye.
View Article and Find Full Text PDFKaposi's sarcoma is a proliferative disease, probably induced by human herpes virus type 8 (HHV8). Its expression is cutaneous and visceral, with four clinical forms. An orbital location of Kaposi's sarcoma remains exceptional.
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