Genetic Determinants and Biofilm Properties Useful in Estimation of UTI Pathogenicity of the Strains Isolated from Free-Living Birds.

: According to the One Health concept, wild birds can be indicators of ecosystem pollution and disease incidence. strains are widespread worldwide, but there are still few reports on the association of human infections with a potential reservoir of highly pathogenic human strains in wild birds. Fecal with uropathogenic potential (UPEC) can be transmitted between birds and humans and may be a risk factor for urinary tract infections (UTIs).

Biodiversity of microorganisms in the Baltic Sea: the power of novel methods in the identification of marine microbes.

Until recently, the data on the diversity of the entire microbial community from the Baltic Sea were relatively rare and very scarce. However, modern molecular methods have provided new insights into this field with interesting results. They can be summarized as follows.

Growth inhibition, oxidative stress and characterisation of mortality in green algae under the influence of beta-blockers and non-steroidal anti-inflammatory drugs.

Bisoprolol and ketoprofen are widely used pharmaceuticals in medical treatment hence these substances are occurring in wastewaters and in water environment. This research investigated the toxic effects of bisoprolol and ketoprofen on two microalgae taxa, Chlorella vulgaris and Desmodesmus armatus. The results showed that both drugs inhibited the growth of the species tested and induced a decrease in chlorophyll a content compared to controls.

Optical method supported by machine learning for urinary tract infection detection and urosepsis risk assessment.

The study presents an optical method supported by machine learning for discriminating urinary tract infections from an infection capable of causing urosepsis. The method comprises spectra of spectroscopy measurement of artificial urine samples with bacteria from solid cultures of clinical E. coli strains.

Asymptomatic Bacteriuria in Kidney Transplant Recipients-A Narrative Review.

Urinary tract infections (UTIs) are the most prevalent complications in kidney transplant (KTx) recipients. The most frequent finding in this group of patients is asymptomatic bacteriuria (ASB). Here, we provide an overview of the available evidence regarding ASB in KTx recipients, including its etiopathology, clinical impact and management.

Surface Topography Description after Turning Inconel 718 with a Conventional, Wiper and Special Insert Made by the SPS Technique.

This paper presents a comparison of surface morphology obtained after machining Inconel 718 by the conventional insert, by Wiper insert and by using the cutting insert made by Spark Plasma Sintering (SPS). The shape of the special insert was obtained by employing Wire Electrical Discharge Machining (WEDM). The paper focuses on the description of surface topography after turning in dry and wet conditions.

Investigation of the Influence of Anti-Wear Coatings on the Surface Quality and Dimensional Accuracy during Finish Turning of the Inconel 718 Alloy.

This piece of work deals with the influence assessment of the kind of coating of the cutting inserts and their wear on the dimensional accuracy and the top layer microstructure and roughness of the surface machined with constant cutting parameters = 85 m/min, = 0.14 mm/obr and = 0.2 mm.

Bisphenol A and its substitutes in the aquatic environment: Occurrence and toxicity assessment.

Bisphenol A is classified as a high production volume chemical commonly used in the manufacture of polycarbonate plastics, epoxy resins and thermal paper. The endocrine disrupting properties of this xenobiotic have led to the restriction and prohibition of its use in many consumer products. To date, many chemical compounds with a chemical structure similar to bisphenol A have been used in consumer products as its replacement.

Surface Topography Description of Threads Made with Turning on Inconel 718 Shafts.

The technology of producing threads, especially in materials that are difficult to cut, is a rare subject of research and scientific publications. The requirements for the production of these elements apply not only to the geometry, but also to the quality of the surface obtained. This is particularly important in the aviation industry, where the durability of the threaded connection affects passenger safety.

Identification of Parameters and Fatigue Life Assessment of the Road Pavement Lower Construction Layers under Heavy Construction Traffic.

This article analyzes the results of testing the subgrade and the lower layers of the pavement structure with the light weight deflectometer at a load of 0.1 and 0.15 MPa.

May Staphylococcus lugdunensis Be an Etiological Factor of Chronic Maxillary Sinuses Infection?

Staphylococcus lugdunensis is an opportunistic pathogen found in the healthy human skin microbiome bacterial community that is able to cause infections of diverse localization, manifestation, and course, including laryngological infections, such as necrotizing sinusitis. Chronic maxillary sinusitis is a disease present in up to one third of European and American populations, and its etiology is not fully described. Within this study, we aimed to characterize 18 S.

Adversarial concept drift detection under poisoning attacks for robust data stream mining.

Continuous learning from streaming data is among the most challenging topics in the contemporary machine learning. In this domain, learning algorithms must not only be able to handle massive volume of rapidly arriving data, but also adapt themselves to potential emerging changes. The phenomenon of evolving nature of data streams is known as concept drift.

Urinary Tract Infections Caused by in Kidney Transplant Recipients - Epidemiology, Virulence and Antibiotic Resistance.

Urinary tract infections are the most common complication in kidney transplant recipients, possibly resulting in the deterioration of a long-term kidney allograft function and an increased risk of recipient's death. has emerged as one of the most prevalent etiologic agents in the context of recurrent urinary tract infections, especially with multidrug resistant strains. This paper discusses the epidemiology and risk factors associated with urinary tract infections in kidney transplant recipients, multi-drug resistance of (ESBL, KPC, NDM), treatment and pathogenesis of infections, and possible causes of recurrent UTIs.

DeepSMOTE: Fusing Deep Learning and SMOTE for Imbalanced Data.

Despite over two decades of progress, imbalanced data is still considered a significant challenge for contemporary machine learning models. Modern advances in deep learning have further magnified the importance of the imbalanced data problem, especially when learning from images. Therefore, there is a need for an oversampling method that is specifically tailored to deep learning models, can work on raw images while preserving their properties, and is capable of generating high-quality, artificial images that can enhance minority classes and balance the training set.

Anomalies in the Geometric Surface Structure of Shaped Elements Composed of Inconel 718 Alloy.

This paper presents the results of investigation that was performed on shafts composed of Inconel 718. Tests were performed in dry and wet conditions. Cutting parameters, such as feed and depth of cut, were constant.

Mapping the metabolomic and lipidomic changes in the bleomycin model of pulmonary fibrosis in young and aged mice.

Alterations in metabolic pathways were recently recognized as potential underlying drivers of idiopathic pulmonary fibrosis (IPF), translating into novel therapeutic targets. However, knowledge of metabolic and lipid regulation in fibrotic lungs is limited. To comprehensively characterize metabolic perturbations in the bleomycin mouse model of IPF, we analyzed the metabolome and lipidome by mass spectrometry.

The Many Faces of spp.-Commensal, Probiotic and Opportunistic Pathogen.

spp. are Gram-positive, facultative, anaerobic cocci, which are found in the intestinal flora and, less frequently, in the vagina or mouth. and are the most common species found in humans.

Evaluating the antibacterial activity of muramyl dipeptide derivatives, retro-tuftsin derivatives, and anthraquinone oligopeptides against a range of pathogenic bacteria.

Search for new and efficient antibiotic is crucial because of microbial drug resistance and problems with side effects of the administered medication. In this study, we evaluate the in vitro microbiological activity of muramyl dipeptide derivatives, retro-tuftsin derivatives (i.e.

XRRpred: accurate predictor of crystal structure quality from protein sequence.

Motivation: X-ray crystallography was used to produce nearly 90% of protein structures. These efforts were supported by numerous sequence-based tools that accurately predict crystallizable proteins. However, protein structures vary widely in their quality, typically measured with resolution and R-free.

X-ray and UV Radiation Damage of dsDNA/Protein Complexes.

Radiation and photodynamic therapies are used for cancer treatment by targeting DNA. However, efficiency is limited due to physico-chemical processes and the insensitivity of native nucleobases to damage. Thus, incorporation of radio- and photosensitizers into these therapies should increase both efficacy and the yield of DNA damage.

Toxic effects of bisphenol A and its analogues on cyanobacteria Anabaena variabilis and Microcystis aeruginosa.

In the last decades, the use of bisphenol A has attracted global attention resulting from its actions as an endocrine disrupting compound. In this regard, various bisphenol analogues have been manufactured as a replacement for this compound in consumer products. As a result of the high production volumes, different bisphenol analogues are entered into the terrestrial and aquatic environment, which consequently leads to their increasing contamination and may pose serious risk to organisms.

The New ST152 Variants with Hypermucoviscous Phenotype Isolated from Renal Transplant Recipients with Asymptomatic Bacteriuria-Genetic Characteristics by WGS.

(Kp) is one of the most important etiological factors of urinary tract infections in renal transplant (RTx) recipients. We described the antimicrobial susceptibility phenotypes and genomic features of two hypermucoviscous (HM) Kp isolates recovered from RTx recipients with asymptomatic bacteriuria (ABU). Using whole genome sequencing (WGS) data, we showed that the strains belong to the ST152 lineage with the KL149 capsular serotype, but without A/A genes, which is typical for HM+ hypervirulent Kp.