Chemical Composition and Lipid Bioactive Components of Dwelling in Bulgaria.

is a plant common in southern Bulgaria. The inflorescences were collected during June and September 2021, while their seeds were obtained in September 2021. The chemical and lipid composition of the inflorescences during the vegetation process of the plant were established.

Assessment of the biological activity of Boiss. ().

Present scientific evidences about the biological activity and potential medical application of extracts derived from Boiss. are limited. Therefore, our study was undertaken to define several main characteristics in this regard - cytotoxicity and antitumor properties, antibacterial activity and immunomodulatory potential.

Metabolic Composition of Methanolic Extract of the Balkan Endemic Species Velen and Its Anti-Inflammatory Effect on Male Wistar Rats.

Extracts from medicinal plants are widely used in the treatment and prevention of different diseases. is a Balkan endemic species with reported antioxidant and antimicrobial characteristics; however, its phytochemical composition is not well defined. Here, we examined the metabolome of by chromatography-mass spectrometry (GC-MS), ultra-performance liquid chromatography-mass spectrometry (UPLC-MS-MS), and inductively coupled plasma mass spectrometry (ICP-MS).

Metabolome Profiling of L. and Boiss Reveals Their Potential as Sources of Plant-Based Pharmaceuticals.

species have been used since ancient times as food additives and curative treatments. Their phytochemical composition and various pharmacological activities were the focus of a number of scientific investigations but no comprehensive metabolome profiling to identify the numerous primary and secondary metabolites has been performed so far. This study aimed to generate a comprehensive picture of the total metabolite content of two species- and -to provide detailed information about the main primary and secondary metabolites.

Design of an Epitope-Based Peptide Vaccine Against the Major Allergen Amb a 11 Using Immunoinformatic Approaches.

Allergic diseases are a socially significant problem of global importance. The number of people suffering from pollen allergies has increased dramatically in recent decades. Pollen allergies affect up to 30% of the world population.

Phytochemical Composition, Antioxidant and Antimicrobial Activity of the Balkan Endemic (Degen) Velen. (Lamiaceae).

The current study investigates the content of sugars, organic acids, phenolic acids and flavonoids, as well as antioxidant and antimicrobial activity of Balkan-endemic . Glucose was the most abundant sugar in the plant (2.77%), followed by fructose (1.