Blood Flow Velocity Analysis in Cerebral Perforating Arteries on 7T 2D Phase Contrast MRI with an Open-Source Software Tool (SELMA).

Blood flow velocity in the cerebral perforating arteries can be quantified in a two-dimensional plane with phase contrast magnetic imaging (2D PC-MRI). The velocity pulsatility index (PI) can inform on the stiffness of these perforating arteries, which is related to several cerebrovascular diseases. Currently, there is no open-source analysis tool for 2D PC-MRI data from these small vessels, impeding the usage of these measurements.

Concussion in Female Athletes of Contact Sports: A Scoping Review.

Background: Recent studies have described higher incidences of concussion, with more severe symptoms and worse outcomes in female athletes compared with male athletes.

Purpose: To compile current knowledge about sex-specific differences in incidence, biomechanics, biomarkers, imaging, and outcomes of concussion in athletes participating in contact sports to better understand which fields should be explored in more detail.

Study Design: Scoping review; Level of evidence, 3.

Safety and function of programmable ventriculo-peritoneal shunt valves: An in vitro 7 Tesla magnetic resonance imaging study.

Objective: The quantity of ultra-high field MRI neuroimaging studies has rapidly increased. This study tests function, safety, and image artifacts of two frequently implanted programmable ventriculo-peritoneal (VP) shunt valves in a 7T MRI system.

Methods: All tests were performed using a whole-body 7T MRI system.

Numerical approach to investigate MR imaging artifacts from orthopedic implants at different field strengths according to ASTM F2119.

Objective: This study presents an extended evaluation of a numerical approach to simulate artifacts of metallic implants in an MR environment.

Methods: The numerical approach is validated by comparing the artifact shape of the simulations and measurements of two metallic orthopedic implants at three different field strengths (1.5 T, 3 T, and 7 T).

Development and evaluation of a numerical simulation approach to predict metal artifacts from passive implants in MRI.

Objective: This study presents the development and evaluation of a numerical approach to simulate artifacts of metallic implants in an MR environment that can be applied to improve the testing procedure for MR image artifacts in medical implants according to ASTM F2119.

Methods: The numerical approach is validated by comparing simulations and measurements of two metallic test objects made of titanium and stainless steel at three different field strengths (1.5T, 3T and 7T).

The traveling heads 2.0: Multicenter reproducibility of quantitative imaging methods at 7 Tesla.

Object: This study evaluates inter-site and intra-site reproducibility at ten different 7 T sites for quantitative brain imaging.

Material And Methods: Two subjects - termed the "traveling heads" - were imaged at ten different 7 T sites with a harmonized quantitative brain MR imaging protocol. In conjunction with the system calibration, MP2RAGE, QSM, CEST and multi-parametric mapping/relaxometry were examined.

Higher sensitivity for traumatic cerebral microbleeds at 7 T ultra-high field MRI: is it clinically significant for the acute state of the patients and later quality of life?

Background: The present study evaluates the possible prognostic benefits of 7 T susceptibility weighted imaging (SWI) of traumatic cerebral microbleeds (TMBs) over 3 T SWI to predict the acute clinical state and subjective impairments, including health-related quality of life (HRQOL), after closed head injury (CHI).

Methods: The study group comprised 10 participants with known TMBs All subjects underwent 3 T magnetic resonance imaging (MRI) and 7 T MRI, respectively. Location and count of TMBs were independently evaluated by two neuroradiologists.

7-T clinical MRI of the shoulder in patients with suspected lesions of the rotator cuff.

Background: To evaluate feasibility and diagnostic performance of clinical 7-T magnetic resonance imaging (MRI) of the shoulder.

Methods: Eight patients with suspected lesions of the rotator cuff underwent 7-T MRI before arthroscopy. Image quality was scored for artifacts, B inhomogeneities, and assessability of anatomical structures.

Adapted cabling of an EEG cap improves simultaneous measurement of EEG and fMRI at 7T.

Background: The combination of EEG and ultra-high-field (7 T and above) fMRI holds the promise to relate electrophysiology and hemodynamics with greater signal to noise level and at higher spatial resolutions than conventional field strengths. Technical and safety restrictions have so far resulted in compromises in terms of MRI coil selection, resulting in reduced, signal quality, spatial coverage and resolution in EEG-fMRI studies at 7 T.

New Method: We adapted a 64-channel MRI-compatible EEG cap so that it could be used with a closed 32-channel MRI head coil thus avoiding several of these compromises.

A network of trans-cortical capillaries as mainstay for blood circulation in long bones.

Closed circulatory systems (CCS) underlie the function of vertebrate organs, but in long bones their structure is unclear, although they constitute the exit route for bone marrow (BM) leukocytes. To understand neutrophil emigration from BM, we studied the vascular system of murine long bones. Here we show that hundreds of capillaries originate in BM, cross murine cortical bone perpendicularly along the shaft and connect to the periosteal circulation.

A 32-channel parallel transmit system add-on for 7T MRI.

Purpose: A 32-channel parallel transmit (pTx) add-on for 7 Tesla whole-body imaging is presented. First results are shown for phantom and in-vivo imaging.

Methods: The add-on system consists of a large number of hardware components, including modulators, amplifiers, SAR supervision, peripheral devices, a control computer, and an integrated 32-channel transmit/receive body array.

European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND).

Introduction: The goal of European Ultrahigh-Field Imaging Network in Neurodegenerative Diseases (EUFIND) is to identify opportunities and challenges of 7 Tesla (7T) MRI for clinical and research applications in neurodegeneration. EUFIND comprises 22 European and one US site, including over 50 MRI and dementia experts as well as neuroscientists.

Methods: EUFIND combined consensus workshops and data sharing for multisite analysis, focusing on 7 core topics: clinical applications/clinical research, highest resolution anatomy, functional imaging, vascular systems/vascular pathology, iron mapping and neuropathology detection, spectroscopy, and quality assurance.

Radiofrequency induced heating around aneurysm clips using a generic birdcage head coil at 7 Tesla under consideration of the minimum distance to decouple multiple aneurysm clips.

Purpose: To evaluate radiofrequency (RF) induced tissue heating around aneurysm clips during a 7T head MR examination and to determine the decoupling distance between multiple implanted clips.

Methods: A total of 120 RF exposure scenarios of clinical relevance were studied using specific absorption rate and temperature simulations. Variations between scenarios included 2 clips (18.

Radiofrequency Coils for 7 Tesla MRI.

Radiofrequency (RF) coils are an essential part of the magnetic resonance (MR) system. To exploit the inherently higher signal-to-noise ratio at ultrahigh magnetic fields (UHF), research sites were forced to build up expertise in RF coil development, as the number of commercially available RF coils were limited. In addition, an integrated transmit body RF coil, which is well-established at MR systems of lower field strength, is still missing at UHF due to technical and physical constraints.

[Safety of implants in high field and ultrahigh field MRI].

Background: It can be expected that the number of 7 T MRI systems for clinical use will increase in the future. On the other hand, almost no medical implant has been labeled MR conditional for 7 T, so far, leaving the question of implant safety unanswered to the MR operator.

Methods: In principle, the same interactions between magnetizable and electric conductive material apply at 7 T as known at lower magnetic field strengths.

Cerebellar transcranial direct current stimulation modulates the fMRI signal in the cerebellar nuclei in a simple motor task.

Background: In a seminal paper, Galea et al. (Modulation of cerebellar excitability by polarity-specific noninvasive direct current stimulation. 2009.

Abdominopelvic 1.5-T and 3.0-T MR Imaging in Healthy Volunteers: Relationship to Formation of DNA Double-Strand Breaks.

Purpose To investigate the relationship between abdominopelvic magnetic resonance (MR) imaging and formation of DNA double-strand breaks (DSBs) in peripheral blood lymphocytes among a cohort of healthy volunteers. Materials and Methods Blood samples were obtained from 40 healthy volunteers (23 women and 17 men; mean age, 27.2 years [range, 21-37 years]) directly before and 5 and 30 minutes after abdominopelvic MR imaging performed at 1.

Doppler ultrasound triggering for cardiac MRI at 7T.

Purpose: A prerequisite for cardiac MR (CMR) imaging is adequate synchronization of image acquisition with the cardiac cycle. Electrocardiogram triggering may be hampered by electromagnetic interferences at high field strength. The purpose of this work is to evaluate the feasibility of Doppler ultrasound triggering for CMR image synchronization at 7T ultra-high-field MRI.

1.5 versus 3 versus 7 Tesla in abdominal MRI: A comparative study.

Objectives: The aim of this study was to investigate and compare the feasibility as well as potential impact of altered magnetic field properties on image quality and potential artifacts of 1.5 Tesla, 3 Tesla and 7 Tesla non-enhanced abdominal MRI.

Materials And Methods: Magnetic Resonance (MR) imaging of the upper abdomen was performed in 10 healthy volunteers on a 1.

Nigrosome 1 visibility at susceptibility weighted 7T MRI-A dependable diagnostic marker for Parkinson's disease or merely an inconsistent, age-dependent imaging finding?

Background: Visualisation of nigrosome 1, a substructure of the healthy substantia nigra, was restricted in susceptibility weighted MR imaging in almost all patients with Parkinson's disease studied so far. The purpose of this study was to determine the degree of visibility of this substructure in subjects without Parkinson's disease and to examine the potential link between increasing brain iron accumulation with age and its detectability.

Methods: In 46 subjects (21 women, 25 men; 19 to 75 y; mean age: 44.

An 8-channel transceiver 7-channel receive RF coil setup for high SNR ultrahigh-field MRI of the shoulder at 7T.

Purpose: In this work, we present an 8-channel transceiver (Tx/Rx) 7-channel receive (Rx) radiofrequency (RF) coil setup for 7 T ultrahigh-field MR imaging of the shoulder.

Methods: A C-shaped 8-channel Tx/Rx coil was combined with an anatomically close-fitting 7-channel Rx-only coil. The safety and performance parameters of this coil setup were evaluated on the bench and in phantom experiments.

Non-enhanced versus low-dose contrast-enhanced renal magnetic resonance angiography at 7 T: a feasibility study.

Background Considering the currently reported association between a repetitive application and cumulative dosage of Gadolinium (Gd)-based contrast agents and Gd-deposition in brain tissue as well as the risk for the advent of nephrogenic systemic fibrosis (NSF), techniques allowing for a dose reduction become an important key aspect aside from non-enhanced magnetic resonance angiography (MRA) techniques. Thus, this study was focused on the reduction and/or complete omission of contrast agent for renal MRA at 7T. Purpose To evaluate the performance of time-of-flight MRA versus low-dose contrast-enhanced (CE) renal MRA at 7T.

7T: Physics, safety, and potential clinical applications.

Unlabelled: With more than 60 installed magnetic resonance imaging (MRI) systems worldwide operating at a magnetic field strength of 7T or higher, ultrahigh-field (UHF) MRI has been established as a platform for clinically oriented research in recent years. Profound technical and methodological developments have helped overcome the inherent physical challenges of UHF radiofrequency (RF) signal homogenization in the human body. The ongoing development of dedicated RF coil arrays was pivotal in realizing UHF body MRI, beyond mere brain imaging applications.