Long-term effect of an enteral diet with a different n-6/n-3 ratio on fatty acid composition and blood parameters in rats.

The n-6/n-3 ratio of polyunsaturated fatty acids (PUFAs) in enteral feeding formulas is not considered to be important, because the short-term administration of these formulas has been the norm for postoperative digestive organs. However, the long-term administration of enteral feeding formulas has been increasingly recommended for patients with aging-associated aphagia. This study is aimed at investigating the effect of the long-term administration of an enteral feeding formula containing n-3 polyunsaturated fatty acids (PUFAs) on the fatty acid composition of endogenous phospholipids.