Polymer concrete is a promising material with applications in construction and architecture; however, guidelines for its design and optimization are not well-established in the literature. This study aimed to evaluate how resin volume fraction and aggregate size distribution affect key properties of polyester polymer concrete, including flexural strength, compressive strength, water absorption, and material cost. Three types of quartz aggregates with different particle size distributions were used, as follows: small (below 0.
View Article and Find Full Text PDFIn this study, a novel lightweight epoxy polymer concrete (PC) was developed with lightweight ceramic aggregates based on waste materials, which can be applied in construction materials. For the purposes of this study, lightweight ceramic aggregates based on waste materials were produced and used as fillers in the production of epoxy polymer concretes. Two aggregate fractions were used in the study: 4-8 mm and 8-16 mm.
View Article and Find Full Text PDFThis viewpoint article presents an opinion about snacks made with lupin species. The nutritional quality of cereal-based snacks increased significantly when lupin was added. For instance, the protein and fibre content of lupin snacks could be as high as 55.
View Article and Find Full Text PDFCancers (Basel)
July 2024
Salvage autologous hematopoietic cell transplantation (auto-HCT) may be used to treat relapse of plasma cell myeloma occurring after previous auto-HCT. When an insufficient number of hematopoietic stem cells have been stored from the initial harvest, remobilization is necessary. Here, we aimed to analyze the efficacy and safety of different doses of cytarabine (total 800 vs.
View Article and Find Full Text PDF-Methyladenosine (mA) is a prevalent and highly regulated RNA modification essential for RNA metabolism and normal brain function. It is particularly important in the hippocampus, where mA is implicated in neurogenesis and learning. Although extensively studied, its presence in specific cell types remains poorly understood.
View Article and Find Full Text PDFComposites based on powdered single-component epoxy matrix are an alternative technological solution for composites produced using liquid epoxy resins. This article describes in detail the process of producing graphite-reinforced composites for tribological applications. The advantages and disadvantages of technological processes where the matrix is a single-component epoxy powder were demonstrated, and the properties of the obtained materials were examined.
View Article and Find Full Text PDFPreterm birth affects approximately 15 million women worldwide, of which 30 % is due to preterm premature rupture of membranes (PPROM). The reasons for shortening the duration of pregnancy are seen in genetic, hormonal, immunological and socio-economic conditions. Recent years have provided a lot of evidence on the impact of the microbiota and whole microbiome on pregnant women, suggesting that the microorganisms inhabiting the vagina significantly affect the risk of preterm delivery.
View Article and Find Full Text PDFDegradation of polymer composites is a significant problem in many engineering aspects. Due to the interaction of various degradation factors during the exploitation of composites, a synergistic effect of destruction is observed. The article describes the phenomena occurring in glass fiber reinforced polyester laminates under the influence of ultraviolet radiation (UV) in an aquatic environment.
View Article and Find Full Text PDFIn this work, epoxy composites filled with flake graphite of various size (less than 10 μm and less than 45 μm) were produced. The aim of the research was to develop a self-lubricating material with favorable tribological properties, i.e.
View Article and Find Full Text PDFNew Medicine Service (NMS) components are an important element to improve patient compliance with medical recommendations. NMS provides support to patients prescribed new medicines, helping them to manage long-term conditions. The purpose of this service is to provide patients with advice, guidelines, and educational materials regarding the use of new medicines to increase patient compliance and therapy safety.
View Article and Find Full Text PDFIntroduction: Electrocardiographic (ECG) patterns suggestive of high-risk coronary anatomy are indications for an urgent invasive approach in non-ST-segment elevation acute coronary syndrome (NSTE-ACS).
Aim: To estimate the frequency of the observed phenomenon and assess the clinical characteristics of NSTE-ACS subjects associated with Wellens syndrome, the de Winter sign, or ST-segment depressions by ≥ 1 mm in ≥ 6 classic ECG leads with simultaneous ST-segment elevation in aVR and/or V1.
Material And Methods: Out of 207 pre-screened subjects diagnosed with NSTE-ACS, 64 patients (26 women and 38 men) with complete medical records (including admission ECG and coronary angiography during the index hospitalization), and significant culprit stenosis or occlusion of the left main coronary artery (LMCA) or the proximal/middle segment of the left anterior descending artery (LAD) entered the final analysis.
The ultimate aim of nuclear reprogramming is to provide stem cells or differentiated cells from unrelated cell types as a cell source for regenerative medicine. A popular route towards this is transcription factor induction, and an alternative way is an original procedure of transplanting a single somatic cell nucleus to an unfertilized egg. A third route is to transplant hundreds of cell nuclei into the germinal vesicle (GV) of a non-dividing Amphibian meiotic oocyte, which leads to the activation of silent genes in 24 h and robustly induces a totipotency-like state in almost all transplanted cells.
View Article and Find Full Text PDFRegeneration is the regrowth of damaged tissues or organs, a vital process in response to damages from primitive organisms to higher mammals. Planarian possesses active whole-body regenerative capability owing to its vast reservoir of adult stem cells, neoblasts, providing an ideal model to delineate the underlying mechanisms for regeneration. RNA N -methyladenosine (m A) modification participates in many biological processes, including stem cell self-renewal and differentiation, in particular the regeneration of haematopoietic stem cells and axons.
View Article and Find Full Text PDFCOVID-19 can lead to severe outcomes in children (1). Vaccination decreases risk for COVID-19 illness, severe disease, and death (2). On December 13, 2020, CDC recommended COVID-19 vaccination for persons aged ≥16 years, with expansion on May 12, 2021, to children and adolescents (children) aged 12-15 years, and on November 2, 2021, to children aged 5-11 years (3).
View Article and Find Full Text PDFIn intelligent transportation, various types of sensors are used both in traffic control systems as well as in the control, safety, and entertainment systems of the vehicles themselves. In the process of educating future designers and developers of such systems, it is necessary to familiarize them with the operation and parameters of sensors. The recent years of the COVID-19 pandemic have disturbed this process due to the need to conduct classes remotely.
View Article and Find Full Text PDFInt J Environ Res Public Health
January 2023
Cardiovascular diseases, particularly coronary heart disease (CHD) caused by atherosclerosis, have the highest worldwide incidence and mortality rate of any type of disease. Aside from risk factors associated with lifestyle and comorbidities, infectious agents such as sensu lato spirochetes, which cause Lyme disease, may also play a role in the development of cardiovascular disease. A growing number of scientific papers have mentioned Lyme carditis.
View Article and Find Full Text PDFThe issues reported in this article concern the development of methods applied for measurement, processing, and analysis of infrasound signals generated in association with the operation of wind farms. In particular, the discussion involves the results of the analysis using synchrosqueezed wavelet transforms of infrasound noise emitted by a 2 MW wind turbine that have been recorded during its operation in actual conditions. To record infrasound signals, a wireless measurement system was used, consisting of a base station and three synchronized mobile recording stations.
View Article and Find Full Text PDFInt J Environ Res Public Health
September 2022
Atypical hemolytic uremic syndrome (aHUS) is a life-threatening disease causing systemic thrombotic microangiopathy (TMA) due to the fact of complement dysregulation. Immune activation by viruses, including SARS-CoV-2, can lead to the development of an episode of aHUS against a background of genetic dysregulation in the complement pathway. This paper presents an analysis of two cases of aHUS-siblings diagnosed with familial disease, with a genetic predisposition to aHUS, in whom infection with SARS-CoV-2 was a strong trigger of disease recurrence.
View Article and Find Full Text PDFThis study was conducted to develop a recombinant Eimeria elongation factor-1α (EF-1α)-vaccination strategy against Eimeria maxima (E. maxima) infection by co-administering with chicken IL-7 (chIL-7) or chicken NK-lysin peptide 2 (cNK-2) in commercial broiler chickens. Chickens were divided into the following 5 groups: control (CON, no Eimeria infection), nonimmunized control (NC, PBS plus Montanide ISA 78 VG), Vaccination 1 (VAC1, 100 µg of recombinant EF-1α plus Montanide ISA 78 VG), Vaccination 2 (VAC2, VAC1 plus 1 µg of chIL-7), and Vaccination 3 (VAC3, VAC2 plus 5 µg of cNK-2 peptide).
View Article and Find Full Text PDFThis work is devoted to evaluating the effectiveness of the recovery of carbon fibers from end-of-life wind turbine blades in the pyrolysis process, and the use of those fibers in the production of flat composite panels. The recovery of carbon fibers from wind turbine blades uses a pyrolysis process at 500-600 °C in a non-oxidizing atmosphere, in such a way that makes it possible to preserve the shape and dimensions of the fibers. Using recycled carbon fibers, flat CFRP sheets with epoxy resin matrix were produced by pressing.
View Article and Find Full Text PDFNaCrO particles for high-rate sodium ion batteries were prepared on a multigram scale in segmented flow from chromium nitrate and sodium nitrate using a segregated flow water-in-oil emulsion drying process. Microfluidic processing is an environmentally friendly and rapid synthetic method, which can produce large-scale industrial implementation for the production of materials with superior properties. The reaction time for NaCrO particles was reduced by almost one order of magnitude compared to a normal flask synthesis and by several orders of magntitude compared to a conventional solid-state reaction.
View Article and Find Full Text PDFVertebrate embryogenesis involves a conserved and fundamental process, called the maternal-to-zygotic transition (MZT), which marks the switch from a maternal factors-dominated state to a zygotic factors-driven state. Yet the precise mechanism underlying MZT remains largely unknown. Here we report that the RNA helicase Ddx3xb in zebrafish undergoes liquid-liquid phase separation (LLPS) via its N-terminal intrinsically disordered region (IDR), and an increase in ATP content promotes the condensation of Ddx3xb during MZT.
View Article and Find Full Text PDFIn this paper, the performance of epoxy/SbSI nanocomposite under tensile stress was investigated. X-ray diffraction studies show the main stress mode has shear nature in the case of elastic deformation, while a combination of shear and tensile stress during plastic deformation caused lattice deformation of SbSI and shift of sulfur atoms along the axis of the unit cell. Apart from that, the piezoelectric signals were recorded during tensile tests.
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