[Absence status epilepticus in adults].

Absence status epilepticus (ASE) is a type of nonconvulsive status epilepticus, in which varying grade of consciousness impairment lasting more than 15 minutes and are accompanied by constant generalized spike-wave complexes with a frequency of 2.5-4 Hz on the electroencephalogram (EEG). ASE can be observed in various epileptic syndromes, usually detected in children.

[Alternative methods of therapy for comorbid sleep disorders as a method of choice in adult patients with epilepsy].

Objective: Systematization and generalization of data from domestic and foreign literature on alternative methods of treatment of sleep disorders in epilepsy.

Material And Methods: The search for data from domestic and foreign literary sources was carried out in the electronic databases Medline (PubMed), Scopus, Web of Science, eLibrary, CyberLeninka, Google Scholar.

Results: The data of modern randomized trials, meta-analyzes on the effectiveness of various non-traditional methods as a method of choice for epilepsy with comorbid sleep disorders have been analyzed.

[The efficacy and tolerability of extended release carbamazepine in adult patients with new-onset epilepsy using epileptiform activity index].

Objective: To evaluate the efficacy and tolerability of extended release carbamazepine (finlepsin-retard and tegretol CR) in adult patients with new-onset focal epilepsy (FE) with the assessment of epileptiform activity index (EAI).

Material And Methods: The study included 62 patients (38 (61.3%) men and 24 (38.

[Sleep and wake disorders in epilepsy].

Objective: To summarize published data on the prevalence, characteristics and diagnostic criteria of sleep disorders in epilepsy.

Material And Methods: A search of published articles was performed in Medline (Pubmed), Scopus, Web of Science and e-library databases.

Results: Epidemiologic, clinical and diagnostic aspects of excessive daytime sleepiness, obstructive sleep apnea and central apnea, restless leg syndrome and parasomnias related to slow-wave and REM-sleep in patients with epilepsy were analyzed.

[Dynamics of epileptiform activity, efficacy and tolerability of valproic acid in adults and adolescents with newly-diagnosed epilepsy].

Objective: To evaluate the changes of epileptiform activity index (EAI) as a measure of the efficacy and tolerability of treatment with valproic acid (VA) in patients with newly-diagnosed generalized and focal epilepsy.

Material And Methods: The study included 93 patients (55 men and 38 women): 27 with focal epilepsy (FE) and 66 with idiopathic generalized epilepsy (IGE). Patients with idiopathic and age-dependent FE were not included in the study.

[Epileptiform activity index for the evaluation of treatment efficacy in patients with epileptic encephalopathy].

Continuous spike and waves during sleep (CSWS) may lead to different cognitive, motor and behavioral symptoms. CSWS is characterized by an electroencephalography (EEG) pattern of electrical status epilepticus during sleep (ESES). The article reviews the main criteria of ESES, localization of EEG-changes and main EEG-patterns.

[ANALYSIS OF RADIATION IN THE DEPLOYMENT OF MILITARY UNITS OF THE MINISTRY OF DEFENSE OF UKRAINE].

There were observed radiation hazardous objects and zone of possibie rauioactive contaminationof the area with military units, and also possibility of influence of adverse factors (radiation) on the human organism. There is also available characteristic of Ukrainian nuclear Powers, number of population, that lives on the area with different pollution degree.

[Intellectual, psychomotor and speech development of children born to mothers with epilepsy].

Intellectual, psychomotor and speech development of 50 children born to mothers with epilepsy were studied. The sample has been stratified into 2 subgroups: children aged from 6 months to 4 years and children aged from 4 to 16 years. This group included 4 (8%) children with children absence epilepsy, juvenile myoclonic and unclassified epilepsy; one patient had a diagnosis of epileptic encephalopathy without epileptic seizures.

[Reproductive potential of women with epilepsy].

An aim of the article was to study reproductive health of 218 women with epilepsy who were long-term treated with antiepileptic drugs (AED). A comparison group included 47 patients with polycystic ovary syndrome (PCOS). Women with epilepsy were stratified into 2 groups: group 1 included 107 women of reproductive age and group 2 - 111 pregnant women with epilepsy.

[Noninvasive video-EEG-monitoring in the diagnosis of focal epilepsy in children].

Unlabelled: Aims of the study include diagnosis of focal epilepsy, determination of localization of interictal and ictal epileptiform activity. 785 patients (age range -- 1 month-21 year) with admission diagnosis "epilepsy" were analyzed. Video-EEG-monitoring using a 21-chanel EEG system with duration 9-96 hours (mean -- 10 hours) was applied.

[Effects of prolonged low-intensity radiofrequency radiation in cm-range on the development of subcutaneously grafted Ehrlich's adenocarcinoma].

White mongrel male mice with subcutaneously grafted Ehrlich adenocarcinoma were exposed at week intervals to three three-day sessions of low-intensity (5 microWt/cm2) super short wave-therapy from two generators of oscillating frequency in the range of 2-18 GHz. As a result of treatment, the increase in tumour size was diminished, and the probability of its reverse development was increased, with animal lethality being decreased. During a month the recovery was increased from 0 to 50% in the first experiment and from 38.

[Radioprotective effect of low-intensity radio-frequency centimeter-band waves in lethal gamma irradiation].

Primary investigations have been carried out to determine whether low-intensity EMR of a cm range exerts the radioprotective effect. Prior to gamma-irradiation with doses LD100/30 and LD60/30 mice were exposed for 23 h to 2-8 GHz microwaves with a swing frequency of 12-14 Hz, at energy flow density of 5 +/- 1.5 mu Wt/cm2.

[Modification of lethal radiation injury in mice by postradiation exposure to low-intensity centimeter-band radio frequency waves].

A clearly pronounced modification of acute radiation injury of mice has been obtained by prolonged action (for up to 23 hours) of low-intensity (5 +/- 1.5 mu Wt/cm2) radiofrequency radiation in the ranges of 2-8, 8-18 and 19-27 GHz with a swing frequency of 12-14 Hz, applied immediately after exposure to lethal dose of gamma-radiation. Survival of mice and average life duration of killed mice were increased.

[An electrophysiological study of the anti-arrhythmia effect of antioxidant ionol].

The paper describes the study of anti-arrhythmia effects of ionol. In isolated rabbit papillary muscle, ionol (a) had no effect on the depolarization-induced automaticity; (b) did not influence early afterdepolarizations: (c) delayed the onset of post-depolarizations initiated by Ca-overload and therefore inhibited the ectopic focal activity in myocardium. In isolated left auricles of rabbit, ionol suppressed the shortening of the excitation wavelength induced with adrenaline and thus protected the heart of reentry and consequent rhythm disturbances.

[Effect of indoleacetic acid on the proton conductivity of biological membranes].

The effect of indolylacetic acid (IAA) on proton conductivity of tylacoid membranes of isolated pea chloroplasts at pH 5.5-8.0 and of artificial phospholipid membranes at pH 7.

[Study of the effect of tegalide and bithionol on biological membranes using fluorescent probes].

Fluorescent probes were used to study structural changes in different membranes affected by gamma-radiation, protonophores and radioprotective agents, tegalide and bithionol. The preparations of the defined concentrations decreased the microviscosity of membranes, lowered the peaks and changed the temperature of phase transitions in liposomes from dipalmitoyl lecithin, and induced the output of Ca2+ from mitochondria. The effects depended on the radiation dose, the structure, concentration and lipophilicity of the preparation; protonophores produced a specific effect.

[Action of new class of substituted salicylanilides on ion conductivity of lipid membranes].

A new class of high-activity substituted salicylanilides has been studied in bilayer lipid membranes (BLM). Very low concentrations of these substances are shown to increase the BLM d. c.

[Protonophoric and uncoupling activity of water-soluble pea flavonols].

In the experiments with artificial lipid membranes and mitochondria the watersoluble pea flavonols are demonstrated to possess weak protonophoric and uncoupling activities which correlate with each other. It is concluded that the mechanism of flavonol uncoupling activity is the same as for classical uncouplers. The results support the earlier suggestion that one of the flavonol functions in the plants may be the regulation of the energetics and metabolism.