[Hygienic aspects of healthy life style development in students].

Medical students have shown a high prevalence of major behavioral factors of health risk, such as inadequate physical activity, changes in the routine, nutrition quality, study-and-rest regimens, as well as smoking and frequent alcohol use. Proposals to educate the students on the importance of living a healthy lifestyle are given.

[Morbidity rates in university students].

The current higher education modernization is accompanied by the intensification of an educational process. Due to intensive mental work and a need to adapt to new educational conditions, the students belong to a group of increased risk. Morbidity rates were studied in medical students during education.

[Hygienic aspects of the lifestyle of medical students under the present conditions].

The paper gives the results of a study of the lifestyle of medical students. The students' motor activity has been found to be lower and to continue to drop in the undergraduates. Examination of the daily routine has shown that 92% of the students break the study-and-rest routine; the reported reasons for this are a high academic load, a prolonged academic day, a study-work combination, mental stress during examinations, and computer-aided learning.

Morphological assessment of the cerebroprotective action of lanthanum acetate in chronic cerebral ischemia in rats.

The aim of the present work was to perform a morphological assessment of the cerebroprotective action of lanthanum acetate in chronic cerebral ischemia in rats. Chronic ischemia was produced in Wistar rats (weighing 160-180 g) by ligation of both common carotid arteries. Ischemic lesions were corrected by intragastric lanthanum acetate (3 mg/kg per day) throughout the experimental period.

[Diet as a factor in the formation of health and working capacity of students].

We have studied 152 students of the Dental faculty. With most of them the caloric content of their daily ration was lower than the energy spent, their body weight was also reduced. The ration of most students had a lowered protein and fat content with prevalence of carbohydrates.

[Epidemiologic and etiologic characteristic of enterovirus infections in Khabarovsk region].

Results of epidemiologic, virologic, and serologic studies of enterovirus infections in Khabarovsk region from 1975 to 2006 were analyzed. Patterns of epidemic process of these infections were established: periodic change of dominating type of pathogen in the population; onset of the large epidemic peaks of incidence during emergence of circulation of new for the given area serotypes of enteroviruses; possibility of realization of several routes of virus transmission. Role of water factor in the progress of the epidemic process was revealed.

[Morphological evaluation of cerebroprotective effect of lanthanum acetate in chronic cerebral ischemia in rats].

The objective of this study was to evaluate morphologically the cerebroprotective effect of lanthanum acetate in chronic cerebral ischemia. Chronic cerebral ischemia was reproduced in Wistar rats, weighing 160-180 g, by a ligation of both common carotid arteries. For corection of ischemic cerebral damage, lanthanum acetate (3 mg/kg of body weight, once a day) was introduced intragastrically during the whole experimental period.

[The effect of 5-bromo-2'-deoxyuridine on the lifespan and behavior of Drosophila melanogaster].

In this study, we have examined the effect of 5-bromo-2'-deoxyuridine incorporated into DNA of Drosophila nerve cells after incubation of larvae in the analog-containing medium on the duration of lifespan and behavior (photoactivity) of adult flies. 5-Bromo-2'-deoxyuridine incorporated into DNA decreases the lifespan of adult animals. In contrast to the control, the curves describing the probability of death become bimodal at higher doses of the analog (above 35 (g/ml).

Optimum collimator for proximity X-ray lithography - Theoretical analysis.

The paper deals with the application of soft X-ray optics to the enhancement of the efficiency of X-ray proximity lithography based on a point X-ray source. The grazing incidence X-ray collimators are shown to increase the efficiency coefficient in several hundreds times. The design of the optimum X-ray collimator is proposed and analysed for the scheme of X-ray proximity lithography with spatial resolution 0.

[Resistance of natural and synthetic polyribonucleotide inducers of interferon to human blood ribonucleases].

The resistance of polyribonucleotide inductors of interferon to blood ribonucleases was studied. Blood resistance of larifan and ridostin in the free and shielded state as well as that of the complexes of poly(I)-poly(C) and poly(G)-poly(C) were also investigated. A protective action of polylysine against the inductors was detected which, in case it had no effect on the biological activity of the drugs, could provide its recommendation as a compound for shielding the inductors.

[Synthesis and analysis of des-Met5-[D-Ala2]enkephalinamide analogs].

The effects of N- and C-terminal oligoalanine insertions into des-Met5-[D-Ala2]enkephalin amide (I) on the biological activity and spatial structure were examined. The corresponding analogues were obtained by solid-phase synthesis using Sephadex LH-20 ac a polymeric support. Biological activity was assayed via changes in the pain threshold in the rat, body temperature, and also as affinity for opiate receptors.

[Antiepileptic action of met-enkephalin and the rapid development of tolerance to its epileptogenic action].

It has been shown in chronic experiments on rabbits with electrochemoelectrodes implanted into the dorsal hippocamp that the first administration of met-enkephalin in a dose of 60 to the hippocamp induced the development of an epileptogenic focus (EF) or potentiated the action of the penicillin-induced EF. The second administration of met-enkephalin in the same dose to the hippocamp (interval in a standard scheme of experiments 5 days) did not lead to the production of the EF, which attests to rapid development of tolerance to the epileptizing action of the peptide, with this tolerance being preserved for 20 subsequent days of observation over the animals. After tolerance developed, administration of 60 micrograms met-enkephalin 5 to 10 min before penicillin produced an antiepileptic action, thereby preventing the development of the EF.

[Decreased acetylcholinesterase activity in the area of epileptogenic foci created by met-enkephalin in the hippocampus of rats].

Experiments on rats with electrochemotrodes implanted in the left and right hippocamp have shown that in epileptogenic foci created by microinjections of met-enkephalin or D-ala-2-met-enkephalin into the hippocamp, acetylcholinesterase activity (AChE) was diminished. It is assumed that reduction in AChE activity is an adaptive mechanism by which the excitability of hippocampal inhibitory basket cells, which are sensitive to acetylcholine, is increased.

[Clinical aspects of the sick sinus syndrome].

Clinico-electrocardiographic studies were carried out in 74 patients with the sick sinus syndrome. The functional tests were used to evaluate the condition of the sinoauricular node (with physical exercise, and dosaged compression of the sinocarotid area). Five variants of the clinical course of the sick sinus syndrome have been distinguished: latent; manifested; the syndrome of bradycardia-tachycardia; the syndrome of sinus bradycardia-auricular bradyfibrillation; constant auricular fibrillation refractor to the treatment including electro-impulse therapy.