Publications by authors named "Koya Okabe"

Article Synopsis
  • * Researchers analyzed data from 3,410 PCI patients between 2010 and 2013, tracking incidences of significant bleeding events (Types 3 or 5) through various bleeding risk scores, including ARC-HBR, PRECISE-DAPT, PARIS, and CREDO-Kyoto.
  • * Results showed that as bleeding risk scores increased, the incidence of bleeding events rose, with ARC-HBR demonstrating greater sensitivity in identifying patients at risk for long-term bleeding compared to the other scores.
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Article Synopsis
  • The study evaluates different high bleeding risk (HBR) definitions (ARC-HBR, S-HBR, and J-HBR) in patients receiving drug-eluting stents, focusing on their effectiveness over time.
  • It found that S-HBR was just as effective as ARC-HBR for predicting short- and long-term bleeding risks, while J-HBR was better for long-term predictions but not as strong for short-term.
  • A total of 3,430 patients were analyzed, and major bleeding occurrences were recorded at 1 and 7 years, revealing slight variations among the definitions' predictive values.
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Background: Gastrointestinal bleeding (GIB) and intracranial bleeding (ICB) are frequently observed as major bleeding events after percutaneous coronary intervention (PCI); however, there are few reports on these predictors and their association with the Academic Research Consortium for High Bleeding Risk (ARC-HBR).

Methods and results: The study included 3,453 patients who underwent PCI with second-generation drug-eluting stents between 2010 and 2013. Mean follow up was 2,663±596 days.

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Background: Percutaneous coronary intervention (PCI) for coronary bifurcation lesions using the 2-stent strategy remains a challenging procedure for interventionalists because of the higher incidence of in-stent restenosis (ISR) and adverse events. ISR predictors in patients treated with newer-generation everolimus-eluting stents (EES) and the 2-stent strategy remain unknown. Hence, we aimed to evaluate the 1-year clinical and angiographic outcomes of non-left main trunk (LMT) bifurcation lesions treated with the 2-stent strategy using newer-generation EES.

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Background: The validity of the Academic Research Consortium for High Bleeding Risk (ARC-HBR) definitions of early (<1 year), late (1-4 years), and very late (>4 years) bleeding events is unknown.

Methods and results: This study was performed on patients (n=3,453) implanted with second-generation drug-eluting stents (DES) between 2010 and 2013. Data on all criteria of the ARC-HBR definition were collected retrospectively.

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Article Synopsis
  • A study analyzed the effects of high-dose statins on cardiovascular outcomes in 1,110 Japanese patients recovering from ST-elevation myocardial infarction (STEMI) between 2011 and 2017.
  • While patients on high-dose statins had higher low-density lipoprotein (LDL) cholesterol levels upon admission, these levels were similar to those on non-high-dose statins by follow-up.
  • The results showed that patients on high-dose statins had significantly lower 2-year incidences of severe cardiovascular events, indicating improved outcomes mainly by reducing the need for revascularization of new lesions.
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Heart failure typically manifests with exertional dyspnea or limb edema. Old age, underlying heart disease, and coronary risk factors are known risk factors for heart failure. Thus, congestive heart failure is rarely considered as a differential diagnosis of chronic cough in a previously healthy young person.

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