Contemporary report of surgical outcomes after single-stage total pancreatectomy: A 10-year experience.

Background: Surgeons rarely perform elective total pancreatectomy (TP). Our study seeks to report surgical outcomes in a contemporary series of single-stage (SS) TP patients.

Methods: Between the years 2013 to 2023 we conducted a retrospective review of 60 consecutive patients who underwent SSTP.

The legacy of social anxiety-linked negative expectancy: A pathway from pre-event negative expectancies to post-event negative thinking.

Background And Objectives: Following engagement in a social event people with heightened vulnerability to social anxiety report elevated levels of negative thinking about the event, and this post-event negative thinking is implicated in the maintenance of social anxiety vulnerability. It has also been established that heightened social anxiety vulnerability is associated with disproportionately negative expectations of upcoming social events. However, contribution of social anxiety-linked pre-event negative expectancy to post-event negative thinking has not been directly investigated.

Anatomic shoulder arthroplasty in Walch type C glenoid deformity: mid- to long-term outcomes.

Background: Hypoplastic glenoid morphology in the setting of glenohumeral osteoarthritis is a rare yet complex surgical problem. Treatment of this patient population with anatomic total shoulder arthroplasty (aTSA) remains controversial. Furthermore, there is no gold-standard approach, with limited guidance for surgeons on the need for glenoid version correction in the setting of a dysplastic glenoid.

Rare occurrence of pseudomyxoma peritonei (PMP) syndrome arising from a malignant transformed ovarian primary mature cystic teratoma treated by cytoreductive surgery and HIPEC: a case report.

Background: Pseudomyxoma peritonei (PMP) syndrome is a disease process that typically occurs from ruptured appendiceal mucocele neoplasms. PMP syndrome arising from malignant transformation of an ovarian primary mature cystic teratoma (MCT) is a pathogenesis rarely encountered.

Case Presentation: Herein, we report a 28-year-old patient evaluated and treated for a right ovarian mass and large volume symptomatic abdominopelvic mucinous ascites.

Mid- to long-term outcomes of augmented and nonaugmented anatomic shoulder arthroplasty in Walch B3 glenoids.

Background: In cases of severe osteoarthritis, posterior glenoid wear leads to acquired retroversion of the glenoid. Surgical treatment of glenoids with acquired retroversion and posterior humeral subluxation with anatomic total shoulder arthroplasty (aTSA) is controversial. The purpose of this study was to determine mid- to long-term outcomes and reoperation rates of augmented and nonaugmented aTSA for treatment of glenohumeral osteoarthritis with Walch B3 glenoid deformity.

Genetic heterogeneity of heritable ectopic mineralization disorders in a large international cohort.

Purpose: Heritable ectopic mineralization disorders comprise a group of conditions with a broad range of clinical manifestations in nonskeletal connective tissues. We report the genetic findings from a large international cohort of 478 patients afflicted with ectopic mineralization.

Methods: Sequence variations were identified using a next-generation sequencing panel consisting of 29 genes reported in association with ectopic mineralization.

Functional Assessment of Missense Variants in the ABCC6 Gene Implicated in Pseudoxanthoma Elasticum, a Heritable Ectopic Mineralization Disorder.

Pseudoxanthoma elasticum, a heritable multisystem ectopic mineralization disorder, is caused by inactivating mutations in the ABCC6 gene. The encoded protein, ABCC6, a transmembrane transporter, has a specialized efflux function in hepatocytes by contributing to plasma levels of inorganic pyrophosphate, a potent inhibitor of mineralization in soft connective tissues. Reduced plasma inorganic pyrophosphate levels underlie the ectopic mineralization in pseudoxanthoma elasticum.

Adherence to home-based videogame treatment for amblyopia in children and adults.

: Home-based videogame treatments are increasingly popular for amblyopia treatment. However, at-home treatments tend to be done in short sessions and with frequent disruptions, which may reduce the effectiveness of binocular visual stimulation. These treatment adherence patterns need to be accounted for when considering dose-response relationships and treatment effectiveness.

Surgical interventions for infantile nystagmus syndrome.

Background: Infantile nystagmus syndrome (INS) is a type of eye movement disorder that can negatively impact vision. Currently, INS cannot be cured, but its effects can potentially be treated pharmacologically, optically, or surgically. This review focuses on the surgical interventions for INS.

Single Muscle Transposition in the Management of Monocular Elevation Deficiency.

Monocular elevation deficiency is characterized by the inability to elevate one eye in abduction, adduction, and primary gaze. To date, various operations, including Knapp's procedure, have been used in the management of hypotropia associated with this condition. However, single muscle transposition has only recently been described as a feasible alternative, offering a number of advantages over other techniques.

Why bilateral medial rectus recession fails? Factors associated with early repeated surgery.

Background: To explore the risk factors for failure of bilateral medial rectus muscle recession (BMR) for esotropia.

Methods: We reviewed 171 consecutive patients with esotropia who underwent bilateral medial rectus muscle recession as a primary procedure from January 2009 to December 2011. Patients with infantile, partially accommodative and acquired esotropia were included.

Optical treatment of amblyopia in older children and adults is essential prior to enrolment in a clinical trial.

Purpose: Optical treatment alone can improve visual acuity (VA) in children with amblyopia, thus clinical trials investigating additional amblyopia therapies (such as patching or videogames) for children require a preceding optical treatment phase. Emerging therapies for adult patients are entering clinical trials. It is unknown whether optical treatment is effective for adults with amblyopia and whether an optical correction phase is required for trials involving adults.

Effectiveness of a Binocular Video Game vs Placebo Video Game for Improving Visual Functions in Older Children, Teenagers, and Adults With Amblyopia: A Randomized Clinical Trial.

Importance: Binocular amblyopia treatment using contrast-rebalanced stimuli showed promise in laboratory studies and requires clinical trial investigation in a home-based setting.

Objective: To compare the effectiveness of a binocular video game with a placebo video game for improving visual functions in older children and adults.

Design, Setting, And Participants: The Binocular Treatment of Amblyopia Using Videogames clinical trial was a multicenter, double-masked, randomized clinical trial.

Conjunctival granuloma post pulley fixation suture.

Pulley fixation sutures to the medial rectus muscles have been used to manage variable-angle esotropia and convergence excess esotropia. Most techniques use a nonabsorbable suture. The posterior location of the sutures usually minimizes complications.

Binocular treatment of amblyopia using videogames (BRAVO): study protocol for a randomised controlled trial.

Background: Amblyopia is a common neurodevelopmental disorder of vision that is characterised by visual impairment in one eye and compromised binocular visual function. Existing evidence-based treatments for children include patching the nonamblyopic eye to encourage use of the amblyopic eye. Currently there are no widely accepted treatments available for adults with amblyopia.

Fixation-linked nondissociated hypotropia: a report of 3 cases.

Fixation-linked hypotropia, or hypotropic dissociated vertical deviation, is a rare but well-defined ocular motility disorder characterized by a slow downward drift of a poor-seeing eye when the other eye is fixating on a distant target. It can be successfully treated with a large recession or recession-resection of the inferior rectus muscle. We report 3 cases of fixation-linked nondissociated hypotropia with unilateral high myopia and amblyopia presenting with intermittent hypotropia of the worse-seeing eye when the dominant eye was fixating on a distant target and a hypertropia of the dominant eye when the poorer-seeing eye was made to fix.

Assessing abnormal head posture: a new paradigm.

Purpose Of Review: We aim to give a systematic approach on how to assess the cause of a patient's abnormal head posture (AHP).

Recent Findings: Over the decades, many important clinical observers and teachers have described diagnostic techniques for patients with AHP. Recently, Wong has added a new set of office-based diagnostic criteria that expand and solidify the office assessment of AHP.

Medial rectus muscle pulley posterior fixation sutures in accommodative and partially accommodative esotropia with convergence excess.

Background: The use of medial rectus pulley posterior fixation sutures to treat esotropia with convergence excess has limited support in the literature. We describe our results using this technique to treat patients with large near-distance disparities.

Methods: We retrospectively analyzed records of patients with accommodative or partially accommodative esotropia and convergence excess 13(Δ) or greater treated with bilateral medial rectus muscle recessions augmented by pulley posterior fixation.

Lateral orbitotomy in the management of challenging exotropia.

The authors present an unorthodox surgical approach to reach the posterior segment of the lateral rectus muscle through a lateral orbitotomy and to manage difficult cases of recurrent exotropia. A review of the records of two patients with recurrent exotropia was done. After an anterior approach had been demonstrated to be inadequate due to shortening or fibrosis of the anterior part of this muscle following repeated surgeries, both patients underwent a lateral orbitotomy to reach the posterior segment of the lateral rectus muscle.

Vestibular, saccadic and fixation abnormalities in genetically confirmed Friedreich ataxia.

Friedreich ataxia (FRDA), the commonest of the inherited ataxias, is a multisystem neurodegenerative condition that affects ocular motor function. We assessed eye movement abnormalities in 20 individuals with genetically confirmed FRDA and compared these results to clinical measures. All subjects were assessed with infrared oculography.

Oxybutynin-associated esotropia.

A 5-year-old girl with previously unrecognized hyperopia of approximately +3.00 D developed esotropia while being treated with oxybutynin for enuresis. The esotropia disappeared with cessation of oxybutynin and correction of her hyperopia.

Botulinum toxin in the treatment of strabismus. A review of its use and effects.

Botulinum Toxin as a medical therapy was introduced by Dr Alan Scott more than 20 years ago. The first clinical applications of Botulinum Toxin type A (BT-A) were for the treatment of strabismus and for periocular spasms. Botulinum Toxin type A is often effective in small to moderate angle convergent strabismus (esotropia) of any cause, and may be an alternative to surgery in these cases.

Chiari 1 malformation presenting as strabismus.

Introduction: Strabismus has been previously reported as a rare presenting feature of the Type 1 Chiari malformation.

Case Reports: We report a case series of twelve patients with Chiari 1 malformations with either strabismus or diplopia as part of their initial presentation. Ten patients had diplopia at the time of presentation, while 2 young children (ages 2 and 6) presented with esotropia without complaints of diplopia.