[Influence of essential oils of plants on mental performance of elderly people.].

The effect of essential oils (EOs) of 22 species and varieties of essential oil plants on the mental performance of elderly people when they inhaled air containing EOs in a gaseous state at a concentration of 1 mg/m3 of air was studied. For the study, a word recognition test with missing letters and a proofreading test were used. It has been established that recognition of words with missing letters is stimulated for a short (10-20 min) duration of exposure to EOs, and then the effect fades away.

Real-World Depression Screening Practices Among Primary Care Providers Across Patient-Level and Provider-Level Characteristics.

This study examined primary care provider (PCP) alignment with guideline-based care for adolescent depression screening and identified factors associated with post-screening responses. A retrospective chart review was conducted across 17 primary care clinics. Logistical regressions were estimated across provider specialties, sociodemographic factors, and patient clinical histories.

[Influence of essential oils of plants on the psycho-emotional state of elderly people.].

The possibility of improving the psycho-emotional state of the elderly by inhaling the vapors of essential oils (EO) of plants at a low concentration (1 mg/m3 of air) has been established. To obtain a quick short-term result, mainly in terms of psychological well-being, EOs of coriander and mountain savory are most suitable. A distant, but more pronounced result in terms of both psychological well-being and psychological tone is given by EO of hyssop officinalis and clove tree.

АNTIMETASTATIC EFFECT OF B. SUBTILIS IMV B-7724 LECTIN OBSERVED IN LEWIS LUNG CARCINOMA MODEL.

Aim: To study the antitumor and antimetastatic effects of B. subtilis IMV B-7724 lectin used in neoadjuvant and adjuvant settings in vivo.

Materials And Methods: Studies were performed on C57Bl/6J mice; Lewis lung carcinoma (LLC) was used as an experimental tumor.

A Method for Microencapsulation of Cells and a Device for Its Realization.

The device for cell encapsulation makes it possible to fabricate microcapsules of a preset size with even smooth surface, without defects or adhesion to each other, with viable cells inside the capsule. The cells were derived from newborn piglet pancreases.

MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models.

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder marked by the loss of motor neurons (MNs) in the brain and spinal cord, leading to fatally debilitating weakness. Because this disease predominantly affects MNs, we aimed to characterize the distinct expression profile of that cell type to elucidate underlying disease mechanisms and to identify novel targets that inform on MN health during ALS disease time course. microRNAs (miRNAs) are short, noncoding RNAs that can shape the expression profile of a cell and thus often exhibit cell-type-enriched expression.

TREM2 variant p.R47H as a risk factor for sporadic amyotrophic lateral sclerosis.

Importance: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which microglia play a significant and active role. Recently, a rare missense variant (p.R47H) in the microglial activating gene TREM2 was found to increase the risk of several neurodegenerative diseases, including Alzheimer disease.

Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice.

microRNAs (miRNAs) are dysregulated in a variety of disease states, suggesting that this newly discovered class of gene expression repressors may be viable therapeutic targets. A microarray of miRNA changes in ALS-model superoxide dismutase 1 (SOD1)(G93A) rodents identified 12 miRNAs as significantly changed. Six miRNAs tested in human ALS tissues were confirmed increased.

Five consecutive cases of a cutaneous vasculopathy in users of levamisole-adulterated cocaine.

Five patients with an antineutrophil cytoplasmic antibody (ANCA)-associated cutaneous vasculopathy secondary to levamisole-adulterated cocaine were prospectively followed up at a single hospital. All patients presented with retiform purpura, with ear involvement being the most characteristic finding. Cocaine metabolites were present on urine toxicology screening, with 2 of 4 of those tested also being positive for levamisole.

Copper-catalyzed N-arylation of imidazoles and benzimidazoles.

4,7-Dimethoxy-1,10-phenanthroline (L1c) was found to be an efficient ligand for the copper-catalyzed N-arylation of imidazoles and benzimidazoles with both aryl iodides and bromides under mild conditions. Further optimization of the system has revealed that the addition of poly(ethylene glycol) accelerates this reaction. A variety of hindered and functionalized imidazoles, benzimidazoles, and aryl halides were transformed in good to excellent yields.

Planning for an annual episodic mass gathering: emergency department and clinic utilization in Yellowstone.

Objective: Planning and providing emergency and primary care for a large transient population of visitors and employees in a national park can be problematic. Furthermore, planning for emergency and primary health care needs of visitors and itinerant workers in a wilderness area national park has not been well documented. A study was performed to analyze emergency and primary health care utilization in a national park.

[Disordered cerebral hemodynamics in diabetic patients (based on myelographic data)].

Overall seventy-six patients with diabetes mellitus (DM) who ranged from 16 to 65 years old were examined. Of these, 62 subjects were given a diagnosis of insulin-dependent DM, 14 insulin-nondependent DM. Moderate severity course of the illness was documented in 32, severe--in 44 patients.

[A lipid metabolic disorder in diabetics].

A total of 52 patients with diabetes mellitus (DM) who ranged from 15 to 60 years old were examined. Of these, 44 had type I DM, eight patients were afflicted with type 2 DM. 77 percent of the examinees were found out to develop hyperlipoproteinemia (HLP), with type 2b HLP having been diagnosed in 80 percent of the patients, type 4 HLP in 20 percent.

[The interrelationship between immune status characteristics and the trace element level in men with ischemic heart disease].

A comparative analysis was carried out between the hair content of basic trace metals in patients with atherosclerosis, ischemic heart disease (IHD) and findings from their immunogrammes. Close correlation was found out between changes in concentrations of Mn, Cu, Fe, Si, Zn, Ca and processes of activation of basic leucocyte populations characteristic of IHD course and alterations in humoral immune response peculiar to the above patients. Conclusions were reached about presence of the aforementioned changes in the pathogenesis of atherosclerosis, IHD.

[Microbial contamination in a water-treatment system].

Microorganisms destructors of organic compounds contained in the Kremenchug reservoir and water treatment system of heat power station have been distinguished and identified. This system does not completely remove microflora at all stages of technological process that results in infestation of ion-exchange resins of the 1st stage filters for water desalting with microorganisms. The reasons have been established of the 1st stage desalting filters infestation by the reservoir water microflora.

[Dermatomycoses in workers in enterprises of the microbiological industry].

Mycologic examination of 54 patients with clinical manifestations of dermatomycosis, engaged in glucose oxidase and catalase production has found a producer fungus, Penicillium vitale in 31 (38%); 3 out of 37 people contacting with producers of glucamylase and pectofetidine appeared to be infected by Aspergillus awamori (1.1%) and Aspergillus foetidus (1.1%), respectively.

[Detection of Coelomomyces psorophorae Couch in the Ukraine].

The narrow-specialized pathogen of blood sucking mosquitoes Coelomomyces psorophorae Couch, which has not been previously found in the territory of the Ukraine, was detected on Aedes cantans and Al. communis larvae in water bodies located in the forest belt of Pushcha-Voditsa (Kiev Polessie, Ukrainian SSR). Evidence on its morphology and ecology is presented.