Pregnancy-induced gait alterations: meta-regression evidence of spatiotemporal adjustments.

During pregnancy, women undergo significant physiological, hormonal, and biomechanical changes that influence their gait. The forward shift of the center of mass and increased joint loads often result in a "waddling gait," elevating the risk of falls. While gait changes during pregnancy have been documented, findings across studies remain inconsistent, particularly regarding variations at different pregnancy stages.

Two-gigapascal-strong ductile soft magnets.

Soft magnetic materials (SMMs) are indispensable for electromechanical energy conversion in high-efficiency applications, but they are exposed to increasing mechanical loading conditions in electric motors due to higher rotational speeds. Enhancing the yield strength of SMMs is essential to prevent the degradation in magnetic performance and failure from plastic deformation, yet most SMMs have yield strengths far below one gigapascal. Here, we present a multicomponent nanostructuring strategy that doubles the yield strength of SMMs while maintaining ductility.

Identifying the Origin of Thermal Modulation of Exchange Bias in MnPS/FeGeTe van der Waals Heterostructures.

The exchange bias phenomenon, inherent in exchange-coupled ferromagnetic and antiferromagnetic systems, has intrigued researchers for decades. Van der Waals materials, with their layered structures, offer an ideal platform for exploring exchange bias. However, effectively manipulating exchange bias in van der Waals heterostructures remains challenging.

Geometric phase analysis of magnetic skyrmion lattices in Lorentz transmission electron microscopy images.

Magnetic skyrmions are quasi-particles with a swirling spin texture that form two-dimensional lattices. Skyrmion lattices can exhibit defects in response to geometric constraints, variations of temperature or applied magnetic fields. Measuring deformations in skyrmion lattices is important to understand the interplay between the lattice structure and external influences.

New Insights Optimize Landing Strategies to Reduce Lower Limb Injury Risk.

Single-leg landing (SL) is often associated with a high injury risk, especially anterior cruciate ligament (ACL) injuries and lateral ankle sprain. This work investigates the relationship between ankle motion patterns (ankle initial contact angle [AICA] and ankle range of motion [AROM]) and the lower limb injury risk during SL, and proposes an optimized landing strategy that can reduce the injury risk. To more realistically revert and simulate the ACL injury mechanics, we developed a knee musculoskeletal model that reverts the ACL ligament to a nonlinear short-term viscoelastic mechanical mechanism (strain rate-dependent) generated by the dense connective tissue as a function of strain.

Harnessing Van der Waals CrPS and Surface Oxides for Nonmonotonic Preset Field Induced Exchange Bias in FeGeTe.

Two-dimensional van der Waals (vdW) heterostructures are an attractive platform for studying exchange bias due to their defect-free and atomically flat interfaces. Chromium thiophosphate (CrPS), an antiferromagnetic material, possesses uncompensated magnetic spins in a single layer, rendering it a promising candidate for exploring exchange bias phenomena. Recent findings have highlighted that naturally oxidized vdW ferromagnetic FeGeTe exhibits exchange bias, attributed to the antiferromagnetic coupling of its ultrathin surface oxide layer (O-FGT) with the underlying unoxidized FeGeTe.

HUNCHEST-II contributes to a shift to earlier-stage lung cancer detection: final results of a nationwide screening program.

Objectives: The introduction of low-dose CT (LDCT) altered the landscape of lung cancer (LC) screening and contributed to the reduction of mortality rates worldwide. Here we report the final results of HUNCHEST-II, the largest population-based LDCT screening program in Hungary, including the screening and diagnostic outcomes, and the characteristics of the LC cases.

Methods: A total of 4215 high-risk individuals aged between 50 and 75 years with a smoking history of at least 25 pack-years were assigned to undergo LDCT screening.

CineScale2: a dataset of cinematic camera features in movies.

The position and orientation of the camera in relation to the subject(s) in a movie scene, namely and , are essential features in the film-making process due to their influence on the viewer's perception of the scene. We provide a database containing camera feature annotations on camera angle and camera level, for about 25,000 image frames. Frames are sampled from a wide range of movies, freely available images, and shots from cinematographic websites, and are annotated on the following five categories - Overhead, High, Neutral, Low, and Dutch - for what concerns camera angle, and on six different classes of camera level: Aerial, Eye, Shoulder, Hip, Knee, and Ground level.

Element-Specific Study of Magnetic Anisotropy and Hardening in SmCoCu Thin Films.

This work investigates the effect of copper substitution on the magnetic properties of SmCo thin films synthesized by molecular beam epitaxy. A series of thin films with varying concentrations of Cu were grown under otherwise identical conditions to disentangle structural and compositional effects on the magnetic behavior. The combined experimental and theoretical studies show that Cu substitution at the Co sites not only stabilizes the formation of the SmCo structure but also enhances magnetic anisotropy and coercivity.

The Origin of the Intracellular Silver in Bacteria: A Comprehensive Study using Targeting Gold-Silver Alloy Nanoparticles.

The bactericidal effects of silver nanoparticles (Ag NPs) against infectious strains of multiresistant bacteria is a well-studied phenomenon, highly relevant for many researchers and clinicians battling bacterial infections. However, little is known about the uptake of the Ag NPs into the bacteria, the related uptake mechanisms, and how they are connected to antimicrobial activity. Even less information is available on AgAu alloy NPs uptake.

Large Interfacial Rashba Interaction Generating Strong Spin-Orbit Torques in Atomically Thin Metallic Heterostructures.

The hallmark of spintronics has been the ability of spin-orbit interactions to convert a charge current into a spin current and vice versa, mainly in the bulk of heavy metal thin films. Here, we demonstrate how a light metal interface profoundly affects both the nature of spin-orbit torques and its efficiency in terms of damping-like () and field-like () effective fields in ultrathin Co films. We measure unexpectedly / ratios much larger than 1 by inserting a nanometer-thin Al metallic layer in Pt|Co|Al|Pt as compared to a similar stacking, including Cu as a reference.

Direct observation of tensile-strain-induced nanoscale magnetic hardening.

Magnetoelasticity is the bond between magnetism and mechanics, but the intricate mechanisms via which magnetic states change due to mechanical strain remain poorly understood. Here, we provide direct nanoscale observations of how tensile strain modifies magnetic domains in a ferromagnetic Ni thin plate using in situ Fresnel defocus imaging, off-axis electron holography and a bimetallic deformation device. We present quantitative measurements of magnetic domain wall structure and its transformations as a function of strain.

A review of different twisted tape configurations used in heat exchanger and their impact on thermal performance of the system.

Heat transfer in water with the help of solar energy is an effective way to harness renewable energy and reduce reliance on non-renewable sources of energy. The utilization of turbulent promoters is an efficient solution to ameliorate the performance of heat exchangers (HE). The current work summarizes the experimental and numerical behaviour of HE reported in the literature, including the thermal examinations of HT and fluid flow characteristics with various turbulent promoters and tube arrangements.

Large-Scale Plasma Proteome Epitome Profiling is an Efficient Tool for the Discovery of Cancer Biomarkers.

Current proteomic technologies focus on the quantification of protein levels, while little effort is dedicated to the development of system approaches to simultaneously monitor proteome variability and abundance. Protein variants may display different immunogenic epitopes detectable by monoclonal antibodies. Epitope variability results from alternative splicing, posttranslational modifications, processing, degradation, and complex formation and possesses dynamically changing availability of interacting surface structures that frequently serve as reachable epitopes and often carry different functions.

Automated recognition of asymmetric gait and fatigue gait using ground reaction force data.

The purpose of this study was to evaluate the effect of running-induced fatigue on the characteristic asymmetry of running gait and to identify non-linear differences in bilateral lower limbs and fatigued gait by building a machine learning model. Data on bilateral lower limb three-dimensional ground reaction forces were collected from 14 male amateur runners before and after a running-induced fatigue experiment. The symmetry function (SF) was used to assess the degree of symmetry of running gait.

Transformation from Magnetic Soliton to Skyrmion in a Monoaxial Chiral Magnet.

Topological spin textures are of great interest for both fundamental physics and applications in spintronics. The Dzyaloshinskii-Moriya interaction underpins the formation of single-twisted magnetic solitons or multi-twisted magnetic skyrmions in magnetic materials with different crystallographic symmetries. However, topological transitions between these two kinds of topological objects have not been verified experimentally.

Hemizygous nonsense variant in the moesin gene leads to a new autoimmune phenotype of Immunodeficiency 50.

Here, we present the findings of an investigation involving two male siblings with juvenile total tooth loss, early-onset chronic leg ulcers, and autoimmune thyroiditis, as well as focal segmental glomerulosclerosis with associated pulmonary emphysema in one and diabetes mellitus in the other. The clinical picture and lupus anticoagulant, cryoglobulin, and cold agglutinin positivity suggested the diagnosis of antiphospholipid syndrome. Flow cytometry analysis showed immunophenotypes consistent with immune dysregulation: a low number of naive T cells, elevated CD4 T cell counts, and decreased CD8 T-cell counts were detected, and more than half of the T-helper population was activated.

Electrostatic Shaping of Magnetic Transition Regions in La_{0.7}Sr_{0.3}MnO_{3}.

We report a magnetic transition region in La_{0.7}Sr_{0.3}MnO_{3} with gradually changing magnitude of magnetization, but no rotation, stable at all temperatures below T_{C}.

Ductile deformation during carbonation of serpentinized peridotite.

Carbonated serpentinites (listvenites) in the Samail Ophiolite, Oman, record mineralization of 1-2 Gt of CO, but the mechanisms providing permeability for continued reactive fluid flow are unclear. Based on samples of the Oman Drilling Project, here we show that listvenites with a penetrative foliation have abundant microstructures indicating that the carbonation reaction occurred during deformation. Folded magnesite veins mark the onset of carbonation, followed by deformation during carbonate growth.

Highly complex magnetic behavior resulting from hierarchical phase separation in AlCo(Cr)FeNi high-entropy alloys.

Magnetic high-entropy alloys (HEAs) are a new category of high-performance magnetic materials, with multicomponent concentrated compositions and complex multi-phase structures. Although there have been numerous reports of their interesting magnetic properties, there is very limited understanding about the interplay between their hierarchical multi-phase structures and the resulting magnetic behavior. We reveal for the first time the influence of a hierarchically decomposed B2 + A2 structure in an AlCoCrFeNi HEA on the formation of magnetic vortex states within individual A2 (disordered BCC) precipitates, which are distributed in an ordered B2 matrix that is weakly ferromagnetic.

Continuous illumination picosecond imaging using a delay line detector in a transmission electron microscope.

Progress towards analysing transitions between steady states demands improvements in time-resolved imaging, both for fundamental research and for applications in information technology. Transmission electron microscopy is a powerful technique for investigating the atomic structure, chemical composition and electromagnetic properties of materials with high spatial resolution and precision. However, the extraction of information about dynamic processes in the ps time regime is often not possible without extensive modification to the instrument while requiring careful control of the operation conditions to not compromise the beam quality.

Unveiling the three-dimensional magnetic texture of skyrmion tubes.

Magnetic skyrmions are stable topological solitons with complex non-coplanar spin structures. Their nanoscopic size and the low electric currents required to control their motion has opened a new field of research, skyrmionics, that aims for the usage of skyrmions as information carriers. Further advances in skyrmionics call for a thorough understanding of their three-dimensional (3D) spin texture, skyrmion-skyrmion interactions and the coupling to surfaces and interfaces, which crucially affect skyrmion stability and mobility.

Detection of leucine-rich alpha-2-glycoprotein 1 containing immunocomplexes in the plasma of lung cancer patients with epitope-specific mAbs.

Background: Lung cancer is the leading cause of cancer-related deaths worldwide. With the expectation of improved survival, tremendous efforts and resources have been invested in the discovery of specific biomarkers for early detection of the disease. Several investigators have reported the presence of cancer-associated autoantibodies in the plasma or serum of lung cancer patients.

Loss of left ventricular rotation is a significant determinant of functional mitral regurgitation.

Aim: To evaluate insufficient rotational movement of the left ventricle (LV) as a potential novel mechanism for functional regurgitation of the mitral valve (FMR).

Methods And Results: We compared reference subjects and patients with LV dysfunction (LVD, ejection fraction EF < 50%) with and without FMR (regurgitant volume RVol>10 ml). Subjects without structural mitral valve pathology undergoing cardiac MRI were evaluated.