Keto-enol Tautomerism of hydroxy-substituted arenes: Theoretical study and experimental consequences.

In this work, the chemical equilibrium between enol and keto tautomers occurring in phenol, naphthols and selected 29 hydroxy substituted polycyclic aromatic hydrocarbons classified into 4 structural types was investigated. The reaction Gibbs energies were computed using the density functional theory combined with the solvent continuum model. We have demonstrated how the consecutive condensation of benzene rings together with two-dimensional molecular arrangement and the position of the hydroxyl group modifies this equilibrium.

The impact of different induction immunosuppression protocols on patient survival, graft survival and acute graft rejection after kidney transplantation.

Objectives: The aim of the study was to stratify the immunological risk based on the presence of risk factors using different induction immunosuppressive protocols.

Background: The path to successful kidney transplantation reflects the accuracy of immunological risk assessment and choice of correct induction and maintenance of immunosuppression to avoid acute kidney rejection.

Methods: We performed a multicentre prospective analysis consisting of patients after kidney transplantation with a 12-month follow-up.

Early recurrence of focal segmental glomerulosclerosis as an unusual cause of primary kidney transplant malfunction.

Recurrence of the primary disease is one of the most common causes of graft failure in the first decade after kidney transplantation. We present a case of a patient with an unusually rapid recurrence of focal segmental glomerulonephritis in the graft, the recognition of its occurrence was hampered by the primary graft affection and oligoanuria and by insignificant histological changes in the first two biopsy samples in the early post-transplant period, as well as by unawareness of the disease leading to terminal renal failure, as no renal biopsy was performed due to grade 3 obesity. Only worsening of hypoalbuminemia and finding of massive proteinuria despite oligoanuria were crucial for further management.

CT findings predicting lung resection in children with complicated community-acquired pneumonia.

Purpose: To investigate computed tomography (CT) features which predict lung resection in children with complicated community-acquired pneumonia.

Methods: A retrospective study of CT findings of patients with complicated pneumonia treated between January 2010 and December 2019. Fisher's exact test and ROC curves were used for statistical analysis.

Older age is a protective factor for academic achievements irrespective of treatment modalities for posterior fossa brain tumours in children.

The treatment of children with posterior fossa brain tumours (PFBT) impacts their long term functional and imaging outcomes. This study aimed to evaluate academic achievement correlated with long-term sequelae after different PFBT treatment modalities. The study cohort consisted of 110 survivors (median age at diagnosis 10.

Further evidence for heredity of pterygium.

Epidemiological reports strongly indicate that pterygium is an ophthalmoheliosis: a sun-related eye disease. Familial occurrence of pterygium is rare but supports the concept that heredity may predispose the conjunctiva to react abnormally to atmospheric-environmental stimuli. We describe a two generation Caucasian family of five members from the United Kingdom, four of whom developed pterygia in early adulthood with autosomal dominant inheritance.

Assessment of clinical biochemical parameters in Roma minority residing in eastern Slovakia compared with the majority population.

Roma constitute the largest ethnic minority in Europe and the second largest minority in Slovakia. Their health problems originate mainly from their low socioeconomic status, certain cultural aspects and their health-threatening lifestyle as well as the psycho-social burden arising from poverty and frequent migration. Evaluation of glucose, albumin, triacylglycerol (TAG) and low density lipoprotein cholesterol (LDL-C) concentrations did not reveal any clue about the presumed deteriorated health of the Roma population.

Glomus jugulare: a rare cause of facial nerve palsy.

Purpose: To report a case of an unusual presentation of a glomus jugulare tumour.

Design: Case report.

Results: Glomus jugulare is a very rare brain tumour that usually presents with tinnitus, hearing loss, dysphagia and hoarseness.

HRTEM studies of amorphous ZrNiTiCu nanocrystalline composites.

Ball milling of easy glass forming Ti(25)Zr(17)Ni(29)Cu(29) alloys lead to the formation of an amorphous structure accompanied by a substantial increase of powder microhardness. The powders show clear glass transition effect and a few stage crystallization starting above 500 degrees C. High-resolution transmission electron microscope technique allowed identifying nanocrystalline inclusions as Cu(12)NiTi(7) within the amorphous powder.

HRTEM studies of NiNbZr + Ag amorphous-nanocrystalline composites.

Amorphous powder of composition corresponding to Ni60Ti20Zr20 (in at%) was obtained by ball milling in a high-energy mills starting from pure elements. Formation of the amorphous structure was observed already after 20 h of milling, although complete amorphization occurred after 40 h. The microhardness of powders increased from about 30 HV for pure elements to above 400 HV (1290 MPa) after 40 h of milling.

HRTEM and TEM studies of amorphous structures in ZrNiTiCu base alloys obtained by rapid solidification or ball milling.

Amorphous structure of Ti(25)Zr(17)Ni(29)Cu(29) composition was studied. Alloys were prepared either by rapid solidification using melt spinning or by high-energy ball milling. The composition of multi-component eutectic in slowly cooled samples of ZrNiTiCu alloy was determined using EDS measurements in scanning microscope of slowly cooled cast samples.

Monitoring of selected "non-hepatic" laboratory parameters in hospitalized cirrhotic patients and their influence on prognosis.

Aim Of The Study: To evaluate the prognostic importance of the analysis of leucocytes, prothrombin time and selected serum biochemical parameters in hospitalized patients with liver cirrhosis.

Patients And Methods: At the Intensive Metabolic Care Unit of 1st Department of Internal Medicine we evaluated 150 patients (87 males, 63 females) with liver cirrhosis at average age: 52.51 +/- 7.

Prognostic importance of the monitoring of selected parameters in liver cirrhosis.

Aim Of The Study: To evaluate the prognostic importance of hepatic encefalopathy and monitoring of transaminase, total and conjugated bilirubine, synthetic liver functions in hospitalized patients with liver cirrhosis.

Patients And Methods: At the Intensive Metabolic Care Unit of 1st Department of Internal Medicine, we evaluated 150 patients (87 males, 63 females) with liver cirrhosis at average age: 52.51 +/- 7.

Sequence similarities and evolutionary relationships of influenza virus A hemagglutinins.

This study brings the analysis of amino acid sequences of hemagglutinin (HA) from the influenza virus A that can infect a wide variety of birds and mammals. 191 sequences belonging to all known 15 HA subtypes were compared. The emphasis was given on functional sites (receptor-binding cavity with its right and left edges) and degree of their conservation in each subtype.

[Effect of passive leg lifting on sodium excretion in patients with liver cirrhosis].

18 healthy subjects and 15 patients with liver cirrhosis were examined using a 2-hour method of passive leg rising (PLR). Renal and hormonal responses to PLR were investigated. There was a significant increase in diuresis (p < 0.

[Hormonal and morphologic characteristics of adrenal incidentalomas].

The authors analyse hormonal and morphological characteristics of adrenal incidentalomas, i.e. pathological adrenal masses accidentally found on CT scan performed due to extraadrenal causes of other causes of adrenal pathology.

[The renin-angiotensin-aldosterone system and serum lipoproteins in patients with essential hypertension].

The authors investigated the relationship between the activity of the renin-angiotensin-aldosterone system and serum lipid levels in patients with essential hypertension (EH). They examined 72 patients with EH stage I and II WHO classification (group A, n = 72, age bracket 16-70 years). They investigated the plasma renin activity (PRA), plasma aldosterone (PA) and total cholesterol (TCH), HDL, LDL cholesterol and triglycerides (TG).

A study of the renal sodium excretion during the normal menstrual cycle using method of passive leg rising.

12 healthy women (age 18-38 years) were examined using the 2-hour's method of passive leg rising (PLR) in follicular (FP) and luteal (LP) phases of normal ovulatory cycle. Renal and hormonal response to PLR was investigated. There was a significant increase of diuresis (from 53 +/- 9 ml/h to 298 +/- 27 ml/h in FP, from 69 +/- 12 to 324 +/- 28 ml/h in LP) and natriuresis (from 4.

Type IV renal tubular acidosis associated with Alport's syndrome.

A case of hereditary nephritis with mild reduction of renal function associated with renal tubular acidosis type IV is described. The patient was admitted with life-threatening hyperkalaemia. To our knowledge, type IV renal tubular acidosis has not been reported previously in association with Alport's syndrome in an adult patient.