Prevalence of carbapenem-resistant Enterobacterales with predominance in hospitals from 2018 to 2021 in Nara, Japan.

Objectives: Despite the global health risk of carbapenem-resistant Enterobacterales (CRE), especially carbapenemase-producing Enterobacterales (CPE), Japan reports a significantly low frequency of CRE with a predominance of IMP-type carbapenemases. This study aimed to investigate the prevalence and characteristics of CRE isolated from hospitals in the city of Nara, Japan.

Methods: We obtained 171 CRE isolates from 16 791 Enterobacterales isolated at 23 hospitals in Nara between January 2018 and December 2021.

Predominance of CTX-M-9 Group Among ESBL-Producing Isolated from Healthy Individuals in Japan.

The detection rate of extended-spectrum β-lactamase (ESBL)-producing Enterobacterales, microorganisms associated with health care settings, has significantly increased worldwide. Moreover, their community incidence has increased in several countries. In this study, we investigated the prevalence and genetic diversity of ESBL-producing isolated from 547 nonduplicated stool specimens from healthy Japanese individuals, between 2015 and 2019.