Hypothalamic pituitary dysfunction after nasopharyngeal carcinoma irradiation.

Purpose: Radiotherapy (RT) is the corner stone of nasopharyngeal carcinoma (NPC) treatment but it exposes to late effects especially hypothalamic pituitary deficiency (HPD). In this article,we aimed to assess the impact of RT on pituitary function in NPC survivors.

Methods: We included 55 patients treated in the radiation oncology department, of Farhat Hached Hospital in Sousse, Tunisia.