A saponin-polybromophenol antibiotic (CU1) from Bark Against Multi-Drug Resistant Bacteria Targeting RNA polymerase.

Background: Gradual increase of multidrug resistant infections is a threat to the human race as MDR plasmids have acquired.>10 mdr and drug efflux genes to inactivate antibiotics. Plants secret anti-metabolites to retard growth of soil and water bacteria and are ideal source of antibiotics.