Development of a novel strategy to understand the impact of shaving on skin health: combining tape strip exfoliation and human skin equivalent technology.

Introduction: The removal of unwanted hair is a widespread grooming practice adopted by both males and females. Although many depilatory techniques are now available, shaving remains the most common, despite its propensity to irritate skin. Current techniques to investigate the impact of shaving regimes on skin health rely on costly and lengthy clinical trials, which hinge on recruitment of human volunteers and can require invasive biopsies to elucidate cellular and molecular-level changes.

Tetra-2,3-pyrazinoporphyrazines with externally appended pyridine rings. 17. Photosensitizing properties and cellular effects of Zn octacationic and Zn/Pt hexacationic macrocycles in aqueous media: Perspectives of multimodal anticancer potentialities.

The photosensitizing activity of two multiply charged porphyrazine derivatives, i.e. the Zn species [(CH)LZn] and the Zn/Pt heterobimetallic complex [(PtCl)(CH)LZn] (neutralized byI ions; L=tetrakis-2,3-[5,6-di(2-pyridyl)pyrazino]porphyrazinato dianion) has been examined in the water medium in the presence of SDS under experimental conditions in which the two species are present exclusively in their monomeric form.