Trends in pathology diagnoses during 10 years of a colorectal cancer screening programme.

Aims: We report pathology findings from the first 10 years of the faecal-occult blood-based Northern Ireland Bowel Cancer Screening Programme, presenting summary data and trends in pathology diagnoses and clinicopathological features of screen-detected cancers.

Methods And Results: Data were analysed from a comprehensive polyp-level pathology database representing all endoscopy specimens from programme inception in 2010 until 2021. A total of 9800 individuals underwent 13 472 endoscopy procedures, yielding 25 967 pathology specimens and 32 119 diagnoses.

Surgery of the small intestine.

The small intestine is the portal of entry of virtually all nutrients and is also the site of diverse inflammatory and neoplastic diseases. This field has recently attracted intense excitement as a result of novel clinical and experimental techniques, combined modality therapies, and basic science applications. This review will highlight important clinical advances in surgery for Crohn disease, short bowel syndrome, transplantation, trauma, and polyposis.

111Indium-labelled red-cell scintigraphy to detect intermittent gastrointestinal bleeding from synchronous small- and large-bowel adenocarcinomas.

A 70-year-old woman presented with symptoms of profound anaemia and evidence of intermittent gastrointestinal haemorrhage. Oesophagogastroduodenoscopy, colonoscopy, abdominal computerised tomography, sulphur colloid scintigraphy and selective mesenteric angiography were non-diagnostic. An indium-labelled red-cell scan was performed, which suggested bleeding from the ileum at 36 h.