Publications by authors named "Kourosh Hayatigolkhatmi"

Article Synopsis
  • * The study proposed an innovative approach by integrating a specialized surface for better cell attachment, a FUCCI(CA)2 sensor, automated image analysis, and a custom machine learning algorithm, allowing accurate measurement of cell cycle phases in non-adherent cells.
  • * The developed automated cell cycle analysis system was validated on leukemia cell lines and is compatible with both non-adherent and adherent cells, making it a valuable free tool for enhancing cancer research and drug development.
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Acute myeloid leukemia (AML) results in disruption of the hematopoietic differentiation process. Crucial progress has been made, and new therapeutic strategies for AML have been developed. Induction chemotherapy, however, remains the main option for the majority of AML patients.

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Background And Objective: β-thalassemia results from a diverse range of mutations inside the hemoglobin subunit β () gene. In a study of β-thalassemia carriers and some of their at-risk fetuses in the Khorasan province of Iran, we aimed to recognize the most common mutations in the region. We also investigated a possible link between these mutations and some of the relevant hematological indices.

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