During the Interwar period (1918-1939), financial aid and technical assistance were given to countries worldwide by the League of Nations Health Organisation (LNHO) in an attempt to reform public health systems, address population health problems, and control infectious diseases. Greece was one of the countries that received this aid, and in 1928 cooperation with the LNHO was initiated. The aim of this alliance was an integrated health reform plan entitled "Collaboration with the Greek government for the sanitary reorganization of Greece" and had a dual purpose: a) the reorganisation of the health services and b) the establishment of a unified public health system that provided comprehensive healthcare for all citizens.
View Article and Find Full Text PDFBackground: The primary goal of therapy for patients with chronic hepatitis C virus (HCV) infection is eradication of HCV ribonucleic acid, which is predicted by achievement of sustained virologic response at 12 weeks (SVR12). Ledipasvir/sofosbuvir was approved by the FDA in 2014 and 2015 as a once-daily regimen for the treatment of HCV genotype 1 and HCV genotypes 4, 5, and 6, respectively. Although its efficacy has been demonstrated in randomized controlled trials, there is an unmet need for real-world effectiveness data and studies that assess the association of rates of SVR12 with specific clinical and demographic factors in the Medicaid population.
View Article and Find Full Text PDFBreast implant-associated (BIA) anaplastic large-cell lymphoma (ALCL) is a rare disease, comprising a small percentage of all non-Hodgkin lymphomas (NHLs), reportedly 2-3%. There is currently no established standard approach to the treatment of BIA ALCL. The first case on the development of ALCL in the presence of a breast implant was reported in 1997 and the association was first identified by the Food and Drug Administration in 2011.
View Article and Find Full Text PDFObjectives: To investigate whether the long term lease of public hospital owned land could be an additional financing mechanism for Greek public (mental) health hospitals.
Methods: We performed a financial analysis of the official 2008 data of a case - study hospital (Mental Health Hospital of Chania). We used a capital budgeting approach to investigate whether value is created for the public hospital by engaging its assets in a project for the development of a private renal dialysis Unit.
Domestic animals are the hosts of several tick species and the reservoirs of some tick-borne pathogens; hence, they play an important role in the circulation of these arthropods and their pathogens in nature. They may act as vectors, but, also, as reservoirs of spotted fever group (SFG) rickettsiae, which are the causative agents of SFG rickettsioses. Q fever is a worldwide zoonosis caused by Coxiella burnetii (C.
View Article and Find Full Text PDFExtrauterine manifestations of endometriosis are well-recognized and frequently encountered by gynecologists, but are not necessarily familiar to the plastic surgery community. With the current increase in gastric bypass procedures performed and the subsequent increase in abdominal wall reconstructions secondary to massive weight loss, the plastic surgeon should have some familiarity with the diverse presentations of this common disease. To help with this, the authors present the case of an abdominal wall endometrioma diagnosed during abdominoplasty.
View Article and Find Full Text PDFBackground: Acute pancreatitis (AP) initiates a generalized inflammatory response that increases intestinal permeability and promotes bacterial translocation (BT). Impairment of the intestinal epithelial barrier is known to promote BT. Glucagon-like peptide 2 (GLP-2), a 33 residue peptide hormone, is a key regulator of the intestinal mucosa by stimulating epithelial growth.
View Article and Find Full Text PDFBackground: The fluorescent marker PKH26 has been demonstrated to be useful for the tracking of endothelial cells in short-term studies; however, the optimal labeling conditions for long-term implants have not been determined. This study was designed to evaluate the effects of PKH26 on endothelial cell proliferation and to identify labeling conditions that would yield the greatest fluorescence over time without adversely affecting cell viability.
Materials And Methods: Canine jugular vein endothelial cells (CJVECs) were labeled with 0.