Publications by authors named "Kouki Honma"
Chloroquine regulates the lipopolysaccharide-induced inflammatory response in RAW264.7 cells.
Allergol Immunopathol (Madr)
July 2024
Article Synopsis
- The study investigates how autophagy impacts the inflammatory response triggered by lipopolysaccharide (LPS) in RAW264.7 cells, focusing on the MyD88/NF-kB signaling pathway.
- Researchers used chloroquine (CQ) as an autophagy inhibitor and found it reduced levels of pro-inflammatory cytokines and influenced other inflammatory mediators in LPS-stimulated cells.
- The findings suggest that CQ could be a potential therapeutic target for managing inflammatory diseases by regulating inflammatory responses.