Complex of Angiotensin II with Modified Low-Density Lipoproteins: Behavioral and Hemodynamic Effects in Rats.

Endogenous multiple modified LDL (mLDL) and the renin-angiotensin system play a significant role in the development of atherosclerosis. It has been found that by behavioral and hemodynamic parameters the physiological activity of angiotensin II (Ang II) in combination with mLDL is considerably modified due to weakening of its diuretic effect and the inversion of hypertensive and tachyarrhythmic effects. Atherosclerosis is a long-term pathological process, so a single administration of artificially synthesized Ang I-mLDL complexes can be considered a model of the first contact of the body with pathogenic factors.

Branchiopoda (Crustacea: Anostraca and Diplostraca) diversity in Tajik Pamir and plain West and South Tajikistan.

Here we attempt to clarify a faunistic composition of branchiopods from southern Tajikistan and the southern part of the Tajik Pamir Plateau (Central Asia) based on samples collected from June 24 to July 6, 2023. In total, 19 species of branchiopods were identified from plain West and South Tajikistan, and 27 species were recorded in Tajik Pamir. Five taxa were newly recorded for the territory of Tajikistan: Chirocephalus cf.

Investigation of the distribution patterns in moinids (Crustacea: Cladocera: Moinidae) forming ephippia with two resting eggs.

During last two decades, morphological and genetic studies of the microcrustaceans from the family Moinidae Goulden, 1968 (Crustacea: Branchiopoda: Cladocera) were intensified. However, species diversity within this family remains underestimated. It refers to both subtropical and tropical areas of different continents that have traditionally been less studied compared with Central Europe and some other Palaearctic regions.

Redescription of Ilyocryptus raridentatus Smirnov, 1989 (Cladocera: Ilyocryptidae).

During recent years, many taxa of water fleas (Crustacea: Cladocera) with wide distribution ranges were revised and finally accepted as groups of cryptic species. Here we provide a redescription of Ilyocryptus raridentatus Smirnov, 1989 (Anomopoda: Ilyocryptidae). Our study clearly confirms that I.

Study of rarely occurring males of Bosminopsis сf. africanus Daday, 1908 (Cladocera: Bosminidae) from SE Asia permits clarification of male-character based differentiation within the genus.

The genus Bosminopsis Richard, 1895 (Cladocera: Bosminidae) is common in the tropics and subtropics of different continents. B. deitersi Richard, 1895 was regarded as a cosmopolitan taxon, but in our previous publications, we have demonstrated the presence of at least four species in the world fauna.

Neural Conversational Agent for Weight Loss Counseling: Protocol for an Implementation and Feasibility Study.

Background: Obesity is a common, serious and costly chronic disease. Current clinical practice guidelines recommend that providers augment the longitudinal care of people living with obesity with consistent support for the development of self-efficacy and motivation to modify their lifestyle behaviors. Lifestyle behavior change aligns with the goals of motivational interviewing (MI), a client-centered yet directive counseling modality.

Essential functions of RNA helicase Vasa in maintaining germline stem cells and piRNA-guided silencing in spermatogenesis.

DEAD-box RNA helicase Vasa is required for gonad development and fertility in multiple animals. Vasa is implicated in many crucial aspects of oogenesis, including translation regulation, primordial germ cell specification, piRNA silencing of transposable elements, and maintenance of germline stem cells (GSCs). However, data about Vasa functions in spermatogenesis remain controversial.

Complete Mitochondrial Genome of Clupeonella abrau (Maliatsky, 1930) (Clupeiformes), an Endemic Freshwater Fish from the Lake Abrau (Russia).

The Abrau sprat (tyulka or sardelka) Clupeonella abrau (Maliatsky, 1930) is an endemic fish of the Lake Abrau (Krasnodar Krai, Russia). The full C. abrau mitochondrial genome (16 650 bp) showed a gene arrangement conserved in Clupeidae and 98.

Molecular Insights into Female Hybrid Sterility in Interspecific Crosses between and .

Species of the genus have served as favorite models in speciation studies; however, genetic factors of interspecific reproductive incompatibility are under-investigated. Here, we performed an analysis of hybrid female sterility by crossing females and males. Using transcriptomic data analysis and molecular, cellular, and genetic approaches, we analyzed differential gene expression, transposable element (TE) activity, piRNA biogenesis, and functional defects of oogenesis in hybrids.

A time-resolved single-cell roadmap of the logic driving anterior neural crest diversification from neural border to migration stages.

Neural crest cells exemplify cellular diversification from a multipotent progenitor population. However, the full sequence of early molecular choices orchestrating the emergence of neural crest heterogeneity from the embryonic ectoderm remains elusive. Gene-regulatory-networks (GRN) govern early development and cell specification toward definitive neural crest.

[Long-term follow-up of adult patients with serial and status course of epileptic seizures].

Objective: To study the follow-up of adult patients with status epilepticus or a history of serial seizures, assessing the likelihood of achieving long-term remission and identifying predictors of treatment effectiveness.

Material And Methods: The study included 280 patients divided into 137 patients with epilepsy with a series of seizures or a history of status epilepticus (group 1) and 143 patients, who had not previously received therapy and did not have a series of seizures or a history of status epilepticus (group 2). A clinical and neurological examination, analysis of medical documentation data, electroencephalography, and MRI were performed.

A new atlas to study embryonic cell types in Xenopus.

This paper introduces a single-cell atlas for pivotal developmental stages in Xenopus, encompassing gastrulation, neurulation, and early tailbud. Notably surpassing its predecessors, the new atlas enhances gene mapping, read counts, and gene/cell type nomenclature. Leveraging the latest Xenopus tropicalis genome version, alongside advanced alignment pipelines and machine learning for cell type assignment, this release maintains consistency with previous cell type annotations while rectifying nomenclature issues.

Nature or number of species in a transition state: the key role of catalytically active molecules in hydrogen transfer stages in atmospheric aldehyde reactions.

For the first time, the two factors (the number of sites in the transition state and the nature of the catalytically active species) that affect the energy barriers ( and Δ) in atmospheric aldehyde reactions are proposed. The contribution of each factor to the energy barriers of the ammonization and amination stages, dehydration, and intramolecular hydrogen transfer is studied using the example of the acetaldehyde and glyoxal interactions with ammonia in aqueous solution. A regular decrease in energy barriers is observed in a series of 4-, 6-, and 8-membered transition states (TSs) regardless of the nature of the catalytically active species and their numbers.

Machine and deep learning methods for clinical outcome prediction based on physiological data of COVID-19 patients: a scoping review.

Introduction: Since the beginning of the COVID-19 pandemic, numerous machine and deep learning (MDL) methods have been proposed in the literature to analyze patient physiological data. The objective of this review is to summarize various aspects of these methods and assess their practical utility for predicting various clinical outcomes.

Methods: We searched PubMed, Scopus, and Cochrane Library, screened and selected the studies matching the inclusion criteria.

Synthesis of Novel Phosphorus-Containing Derivatives of 1,3,4-Trimethylglycoluril via the Birum-Oleksyszyn Reaction.

This work presents the synthesis of a new compound, 1-[aryl-(diphenylphosphono)methyl]-3,4,6-trimethylglycolurils, via the interaction of benzaldehyde and its mononitro- and monohydroxyderivatives with 1,3,4-trimethylglycoluril and triphenylphosphite. By varying the reaction conditions and the catalysts, the obtained product yields ranged from satisfactory to good. The diastereomers formed during the reaction were separated by semipreparative HPLC on the C18 stationary phase.

Light antiproton one-electron quasi-molecular ions within the relativistic A-DKB method.

In the present work, two quasi-molecular compounds each involving one antiproton and one electron (p̄), He+-p̄ and H-p̄, are investigated. Using completely relativistic calculations within the finite-basis method adapted to systems with axial symmetry, the adiabatic potential curves are constructed by numerically solving the two-center Dirac equation. The binding energies of electron are obtained as a function of the inter-nuclear distance and compared with the corresponding nonrelativistic values and relativistic leading-order corrections calculated in the framework of other approaches.

[The effect of the start date of cognitive rehabilitation after ischemic stroke on the level of recovery].

Objective: The dependence of result of cognitive training in patients who have suffered an ischemic stroke (IS) on the timing of their onset continues to be discussed. The aim was to study the results of cognitive rehabilitation of patients after IS during various periods after it.

Material And Methods: 140 patients were examined during complex rehabilitation in terms up to 1, 2-3, 4-6 and 7-12 months after IS, 78 of them received drug support (DS) of rehabilitation with intravenous injections of ampasse.

The Instrumental Role of Strategic Communication to Counter Industry Marketing Responses to Sugary Drink Taxes Comment on "Understanding Marketing Responses to a Tax on Sugary Drinks: A Qualitative Interview Study in the United Kingdom, 2019".

Strong sugary drink taxes are effective at reducing sugary drinks consumption. In response, the sugary drinks industry employs various marketing strategies to undermine the taxes to protect and maintain its customer base. In their recent article in this journal, Forde et al present a framework for understanding how sugary drinks companies use marketing for this purpose.

A new species of the genus Ceriodaphnia Dana, 1853 (Cladocera: Daphnidae) from Eastern Siberia (Russia) that combines morphological features of two species groups.

Taxa of the genus Ceriodaphnia Dana, 1853 (Cladocera: Daphniidae) are ubiquitous in temperate and tropical lakes, and the taxonomy of the genus is confused. Moreover, present keys are often regional and insufficient for the taxonomic assignment of species at a global scale. This communication is aimed at improving our understanding of the C.

RNA Helicase Vasa as a Multifunctional Conservative Regulator of Gametogenesis in Eukaryotes.

Being a conservative marker of germ cells across metazoan species, DEAD box RNA helicase Vasa (DDX4) remains the subject of worldwide investigations thanks to its multiple functional manifestations. Vasa takes part in the preformation of primordial germ cells in a group of organisms and contributes to the maintenance of germline stem cells. Vasa is an essential player in the piRNA-mediated silencing of harmful genomic elements and in the translational regulation of selected mRNAs.