Publications by authors named "Kotomi Sakai"
Purpose: This systematic review analyzes economic evaluations of newborn screening for congenital cytomegalovirus (cCMV) infection to identify key factors influencing cost-effectiveness and differences in methodological approaches.
Methods: Following a pre-registered PROSPERO protocol (CRD42023441587), we conducted a comprehensive literature search across multiple databases on July 4, 2024. The review included both full economic evaluations (cost and outcomes) and partial economic evaluations (cost only).
Objective: The potential link between malnutrition and dysphagia along with its underlying mechanisms remains unknown. This study aimed to investigate the association between malnutrition factors and dysphagia mediated by a decline in activities of daily living (ADL) among nursing home residents.
Methods: This cross-sectional study used data from 705 nursing home residents.
Aim: In Japan's public health system, dentists can assess and intervene in oral hypofunction cases. However, the associations between oral hypofunction and health outcomes and costs remain unclear. This study aimed to identify these associations.
View Article and Find Full Text PDFBackground: Stroke patients often face disabilities that significantly interfere with their daily lives. Poor nutritional status is a common issue amongst these patients, and malnutrition can severely impact their functional recovery post-stroke. Therefore, nutritional therapy is crucial in managing stroke outcomes.
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- Spending time out of bed is crucial for older adults to prevent functional decline.
- A study with 748 participants aged 65 and older revealed significant links between time away from bed and oral hygiene/function issues.
- Findings suggest that enhancing the time older adults spend out of bed could improve their oral health and overall well-being.
Background: This study analyzed data from the Long-term care Information system For Evidence (LIFE) database to examine the effects of motivation to eat, appetite and food satisfaction, and food consciousness on food intake and weight loss.
Methods: Of the 748 nursing home residents enrolled in the LIFE database, 336 met the eligibility criteria for this cross-sectional study. Motivation to eat, appetite and food satisfaction, and food consciousness were rated on five-point Likert scales (e.
Article Synopsis
- Fan therapy is a non-drug method that helps alleviate shortness of breath in terminally ill patients by directing airflow on one side of their face.
- A scoping review was conducted to explore existing studies on fan therapy, focusing on its safety and methods, as there have been no comprehensive reviews specific to critically ill patients in intensive care units.
- Out of 685 initial studies, 15 were included in the review, with most focusing on patients with terminal cancer and chronic lung diseases, indicating that fan therapy is generally safe and beneficial, although its application in critically ill patients remains unstudied.
Whether or not conditions should be included in publicly funded newborn screening (NBS) programs should be discussed according to objective and transparent criteria. Certain criteria have been developed for the introduction of NBS programs in the context of individual countries; however, there are no standard selection criteria for NBS programs in Japan. This study aimed to develop a quantitative scoring model to assess newborn screening that incorporates the views of a variety of stakeholders in Japan.
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- Biliary atresia (BA) is a rare liver disease in children that requires timely surgical treatment, specifically the Kasai procedure (KP), to improve outcomes.
- The systematic review and meta-analysis of studies from 1968 to May 2022 focused on the timing of the KP and its impact on native liver survival (NLS) rates, revealing that patients undergoing the procedure after 30 days had a quicker need for liver transplantation.
- The findings highlight the significance of early diagnosis and intervention for BA, recommending newborn screenings to ensure that surgery is performed ideally within the first 30 days of life to enhance long-term liver survival.
Objective: To evaluate the cost-effectiveness of universal newborn screening using stool color card or direct bilirubin (DB) testing when comparing with no screening for biliary atresia in Japanese setting.
Study Design: A decision analytic Markov microsimulation model was developed to evaluate the universal screening for biliary atresia. Our screening strategies included stool color card, DB, or no screening.
Repetitive peripheral magnetic stimulation for impairment and disability in people after stroke.
Cochrane Database Syst Rev
September 2022
Background: Repetitive peripheral magnetic stimulation (rPMS) is a non-invasive treatment method that can penetrate to deeper structures with painless stimulation to improve motor function in people with physical impairment due to brain or nerve disorders. rPMS for people after stroke has proved to be a feasible approach to improving activities of daily living and functional ability. However, the effectiveness and safety of this intervention for people after stroke remain uncertain.
View Article and Find Full Text PDFStrategies for cost-effectiveness analysis of rehabilitation for older patients with acute heart failure.
Cost Eff Resour Alloc
September 2022
The prevalence of heart failure (HF) is increasing in the ageing world population, and its burden on the medical and health economic fields is enormous. Rehabilitation is an essential component of the nonpharmacological treatment of patients with HF; however, its efficacy and cost-effectiveness for patients with acute HF remain unclear. A trial assessed the cost-effectiveness of acute cardiac rehabilitation among older adults.
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- A systematic review was conducted to explore the links between oral function, dysphagia, frailty, and sarcopenia in older adults living in the community, as previous studies hadn't been summarized comprehensively.
- The review included 24 studies (20 cross-sectional and 4 prospective cohort) and found that older adults with frailty or sarcopenia exhibited significantly lower tongue pressure.
- Additionally, frailty was associated with a higher likelihood of dysphagia, but inconclusive results were found regarding sarcopenia's association with dysphagia; overall, reduced oral function and dysphagia may be key indicators of frailty and sarcopenia in older adults.
Article Synopsis
- * Researchers photographed the anterior neck of patients to analyze features related to sarcopenic dysphagia and used these images along with patient data (age, sex, BMI) to create predictive models.
- * Results showed that the best predictive model had strong performance with an ROC-AUC of 0.877, demonstrating the effectiveness of this image recognition approach for screening sarcopenic dysphagia.
Article Synopsis
- * A scoping review analyzed 22 studies to identify key nutritional assessment categories, finding that BMI and albumin were the most frequently evaluated metrics.
- * The research recommends using the Global Leadership Initiative on Malnutrition (GLIM) criteria for nutritional assessments in dysphagia patients to promote standardization and improve future outcomes.
Purpose: The objectives of this study were two-fold: 1) to investigate differences in activity duration and amplitude of the submental muscles during swallowing measured with surface electromyography (sEMG) in older patients with sarcopenic dysphagia compared to those without dysphagia and 2) to examine the diagnostic accuracy of submental sEMG signals for sarcopenic dysphagia.
Patients And Methods: Patients (n = 60) aged ≥65 years participated in this cross-sectional study. The submental muscle activity duration parameters were the duration from the onset of swallowing to the maximum amplitude (duration A), duration from the maximum amplitude to the end of the swallowing activity (duration B), and total duration.
The aim of this systematic review was to assess the best available evidence on semi-solid nutrients for prevention of complications associated with enteral tube feeding (ETF). PubMed (MEDLINE), EMBASE, Cochrane Central Register of Controlled Trial, Ichushi-web, and World Health Organization International Clinical Trials Registry Platform databases were searched for relevant articles. Randomized controlled trials (RCTs), cluster RCTs, and crossover trials comparing the effects of semi-solid nutrients with those of control interventions in patients on ETF were included in the review.
View Article and Find Full Text PDFRepetitive peripheral magnetic stimulation for impairment and disability in people after stroke.
Cochrane Database Syst Rev
November 2019
Background: Repetitive peripheral magnetic stimulation (rPMS) is a non-invasive treatment method that can penetrate to deeper structures with painless stimulation to improve motor function in people with physical impairment due to brain or nerve disorders. rPMS for people after stroke has proved to be a feasible approach to improving activities of daily living and functional ability. However, the effectiveness and safety of this intervention for people after stroke currently remain uncertain.
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- Dysphagia in older adults can be linked to sarcopenia, with this study aiming to explore how lip force and tongue strength relate to this condition and their diagnostic value.
- A total of 245 inpatients aged 65 and older were assessed for sarcopenic dysphagia, alongside factors like cognitive function and nutritional status, using logistic regression for analysis.
- Results showed that patients with sarcopenic dysphagia had significantly lower lip force and tongue strength, indicating these measures can effectively identify the condition, particularly with high diagnostic accuracy in both sexes.
Objective: The objective of this study was to clarify the relationship between tongue strength, lip strength, and nutrition-related sarcopenia (NRS).
Patients And Methods: A total of 201 older inpatients aged ≥65 years (70 men, median age: 84 years, interquartile range: 79-89 years) consecutively admitted for rehabilitation were included in this cross-sectional study. The main factors evaluated were the presence of NRS diagnosed by malnutrition using the Mini-Nutrition Assessment - Short Form, sarcopenia based on the criteria of the Asian Working Group for Sarcopenia, tongue strength, and lip strength.
The aim of this cross-sectional study was to investigate whether tongue strength observed in older adult inpatients of a rehabilitation hospital is associated with muscle function, nutritional status, and dysphagia. A total of 174 older adult inpatients aged 65 years and older in rehabilitation (64 men, 110 women; median age, 84 years; interquartile range, 80-89 years) who were suspected of having reduced tongue strength due to sarcopenia were included in this study. Isometric tongue strength was measured using a device fitted with a disposable oral balloon probe.
View Article and Find Full Text PDFReal-world Effectiveness of Speech Therapy Time on Cognitive Recovery in Older Patients with Acute Stroke.
Prog Rehabil Med
September 2016
Objective: The purpose of this research was to investigate the real-world effectiveness of speech therapy time on cognitive recovery in older patients with acute stroke.
Methods: The participants of this retrospective cohort study were hospitalized patients with acute stroke registered in the Japan Rehabilitation Database between December 2005 and September 2014. The patients were divided into two groups according to the amount of time they spent undergoing speech therapy, i.