[State of physiological anticoagulant heparin, antithrombin III and their correction with medicines in patients with acute viral myocarditis].

For the first time, positive influence was shown of a complex blood heparin-antitrombin III on the state of the coagulant and fibrinolytic system of blood in patients with acute virus myocarditis that favours the normalization of clinical and laboratory indicators, improvement of the state of patients and reduction of average bed-day indicator (hospital stay) till 25 and 35 days in accordance with severity of clinical course of the disease and can be recommended as a choice of medicine.

[Enzymatic (plasmin) blood system in patients with acute virus myocarditis and its medical correction].

For the first time it is established that changes of parametres of coagulation hemostasis (fibrinogen Fg, soluble complexes of monomeasured fibrin -SCMF, products of fibrin degradation-PFD, 1st and 2nd waves of platelet aggregation), platelet hemostasis (platelets, a range index of platelet contact activation -RIPCA, activated partial platelet time--APPT, a total index thrombophilia TIT, platelet time--PT, prothrombin time (Prv), physiological anticoagulants (blood heparin-BH, antithrombin III--AT III, plasma tolerances to heparin--PTH), and fibrinolysis (lysis time of euglobulin clot--LTEC), enzyme condition of antiradical protection--superoxide scavenger (SOSC) which reduction in concentration leads to increase in concentration of malonic dialdehyde (MD) in erythrocytes (Er), thrombocytes (Tr), blood plasma (BP) in patients with acute virus myocarditis (AVM) of all severity groups and statistically correlate with the degree of severity of clinical course and demands medication correction.

[Coagulative hemostasis in patients with acute viral myocarditis].

For the first time it was established that changes of fibrinogen parameters, dissolved complexes of monomeric fibrinogen (DCMF), products of fibrinogen degradation (PDEF), first and second waves of platelet aggregation, activated partial platelet time (APPT), range index of contact platelet activation (RICPA), general index of thrombophilia (GIT), platelets, prothrombin time, heparin in blood, plasma tolerance to heparin (PTH), time lysis and euglobulin clot (TLEC), lipid peroxidation, antiradical defence ferment, superoxiddismutase (SOD) in patients with acute virus myocarditis of first, second and third group of severity correlate statistically reliably with grade of severity of clinical course of the disease and require correction with medications.

[Total index of thrombocyte aggregation in patients with an acute viral myocarditis].

For the first time it is proved, that patients with an acute virus myocarditis have statistically confirmed authentic reduction in quantity of thrombocytes, extention of parameters of a activated partial thrombin time, reduction in concentration of a heparin-antithrombin III (AT-III) complex against suppressed enzyme of antiradical protection - superoxide dismutase and it has led to activization of a malonic dialdehyde in erythrocytes, thrombocytes and blood serum. In case of the development of an acute virus infection especially caused cardiotrophic strain Consaki, virus CVB 1-CVB 4, thrombocytes, according to P. Nemetchek-Gansler, acquire not pertaining to them ability for phagocytosis of viruses with following reduction in quantity of thrombocytes and increase in aggregation abilities of thrombocytes what influence the state of duration index of contact aggregation of thrombocytes with the tendency to shorten this duration, and also it may develop hypoxia, an ischemia and the subsequent necrosis of cardiomyocytes, that is to an acute virus myocarditis that demands corresponding correction with medications.

[Use of enterosorption for correction of dyslipoproteinemias in patients with ischemic heart disease in geriatric practice].

Sixty patients with coronary heart disease, stable angina pectoris of functional class II and III and dislipoproteinemia (cholesterol greater than 6.5 mmol/l, triglycerides greater than 2.0 mmol/l, the atherogenic index greater than 3.

[Correction of dyslipoproteinemia in middle-aged and elderly patients with atherosclerosis using Essentiale in combination with adebit].

A combination of Essentiale and adebit was used in the treatment of 62 patients (age: 60-89 years) with stable stenocardia. Essentiale normalizes the cholesterol metabolism, adebit normalizes the carbohydrate metabolism. Results of the treatment indicate that elderly and old, in particular, showed an improvement of the clinical condition of the disease, normalization of the lipid metabolism.

[The cardiovascular system of healthy long-living Abkhazians].

In order to study the peculiarities of aging of the blood circulatory system, an epidemiological investigation of long-living humans (subjects aged 90 years and over) was performed in three villages of Abkhazia. The region is characterized by a high level of longevity. Seventy-eight long-living individuals were available for the study.

[Functional age of the cardiovascular system and its assessment by age equivalents].

The method for biological (functional) age assessment of the blood circulation system has been developed from the age equivalent value estimated on the basis of a number of indices reflecting the function of a given system. For mathematical processing discriminant analysis was used. Formulae illustrating the biological (functional) age assessment of the human cardiovascular system are presented.

[Prognosis of the probable morbidity rate in ischemic heart disease in patients over 50].

A mathematic model on prognostic statements as to the development of the ischaemic heart disease from the 50th year of life has been developed. By applying the probit analysis it was possible to plot curves which contain statements on the probable morbidity rate with regard to the ischaemic heart disease. The probability of becoming affected by the ischaemic heart disease increases with advancing years both in men and women.

[Peculiarities of unconditioned and conditioned reflex stimuli effects on secretory function of gastric glands in elderly and senile people (author's transl)].

For understanding age peculiarities of gastric secretory function in aging.tory function in aging.tory function regulation, the investigation of nervous influences on gastric secretion is of importance.