Analysis of dose-dependent effect of zinc oxide nanoparticles on the oxidative stress and antioxidant enzyme activity in adipocytes.

The present study aimed to synthesize Zinc oxide (ZnO) nanoparticles and to analyze the dose-dependent effect on the oxidative stress and antioxidant enzyme activities in 3T3-L1 adipocytes. ZnO is widely used in the several cosmetic lotions and biomedical products. There are several studies that have reported the ZnO nanoparticle-mediated cytotoxicity on various tissues.

Effects of stress hormone cortisol on the mRNA expression of myogenenin, MyoD, Myf5, PAX3 and PAX7.

The present investigation was carried out to evaluate the effect of stress hormone cortisol on the myogenic markers in the C2C12 cells co-cultured with 3T3-L1 preadipocytes. Co-culturing was achieved by transwell inserts with a 0.4 μm porous membrane.