Structural and antigenic characterization of a novel genotype of Mfa1 fimbriae in .

Background: Mfa1 fimbriae of the periodontal pathogen Porphyromonas gingivalis are responsible for biofilm formation and comprise five proteins: Mfa1-5. Two major genotypes, mfa1 and mfa1, encode major fimbrillin. The mfa1 genotype is further divided into the mfa1 and mfa1 subtypes.

Diversity analysis of genes encoding Mfa1 fimbrial components in Porphyromonas gingivalis strains.

Porphyromonas gingivalis, a gram-negative anaerobic bacterium, is associated with the development of periodontal disease. The genetic diversity in virulence factors, such as adhesive fimbriae, among its strains affects the bacterial pathogenicity. P.