Alterations between high and low-avoidance lines of Hatano rats in learning behaviors, ultrasonic vocalizations, and histological characteristics in hippocampus and amygdala.

Growing evidence supports interactions between anxiety and cognitive function. The primary object of this study was to elucidate whether high-avoidance (HAA) and low-avoidance (LAA) strains of Hatano rats are suitable for the analysis of interactions between the formation of long-term memory and emotional reactivity. The learning/memory ability of Hatano rats and their Sprague-Dawley (SD) ancestors was evaluated using contextual fear conditioning, Y-maze, and Barnes maze tests from 8 weeks of age.

[Psoriasis and Psoriatic Arthritis Induced by Nivolumab in a Patient with Advanced Non-Small-Cell Lung Cancer].

Background: Immune checkpoint-blocking antibodies may induce specific side effects known as immune-relatedad verse events.

Case Presentation: A 66-year-oldman without any history of autoimmune disease was referredto our hospital for treatment of lung cancer in the right upper lobe. The tumor was diagnosed as Stage III A non-small-cell lung cancer by using bronchoscopic biopsy, computedtomography, andFDG -PET.