Measurement of vitamin D-binding protein in pleural fluids and sera by means of a turbidimetric immunoassay measuring system.

Background: Vitamin D-binding protein (DBP) has been recognized as a multifunctional plasma protein that can modulate certain immune and inflammatory responses. There may be differences between the DBP concentrations in pleural fluids from various diseases involving a variety of possible responses in the pleural cavity.

Methods: An anti-DBP polyclonal antibody was prepared using commercially available DBP to establish a quantitative measuring system for DBP.