Involvement of strawberry notch homologue 1 in neurite outgrowth of cortical neurons.

When the regulation of axonal and dendritic growth is altered, the neuronal network becomes disordered, which may contribute to the development of psychiatric disorders. Some genome analyses have suggested relationships between mutations in strawberry notch homologue 1 (SBNO1) and neurodevelopmental disorders. However, the function of SBNO1 has not yet been reported.

Dab1 contributes differently to the morphogenesis of the hippocampal subdivisions.

The hippocampal formation (HF) is morphologically and functionally distinguishable into the subdivisions, such as the dentate gyrus (DG), subiculum, and Ammon's horn. The Ammon's horn is further divided into the CA (Cornu Ammonis)1, CA2, and CA3. The Reelin-Dab1 signal is essential for the morphogenesis of the mammalian brain.

A mammalian dpy-19 homologue is expressed in GABAergic neurons.

Gsh2 homeobox transcription factors play a crucial role in the development of GABAergic neurons. Caenorhabditis elegans's mab-5 gene is homologous to Gsh2; its expression is controlled by dpy-19. This study produced the polyclonal anti-mammalian DPY-19 (MDPY-19) antibody and showed the distribution of anti-MDPY-19 immunopositive cells.