Publications by authors named "Kosuke Shabana"
Article Synopsis
- - This systematic review evaluated how effective and safe tumor necrosis factor (TNF) inhibitors are for treating systemic juvenile idiopathic arthritis (JIA) by examining various studies from 2000 to 2021.
- - The review included one randomized controlled trial (RCT) and 22 observational studies, with the RCT showing that infliximab had moderate efficacy (ACR Pediatric responses of about 63.8% at 14 weeks) but also reported significant side effects like anaphylaxis in 17% of patients.
- - The findings suggest that while TNF inhibitors appear relatively safe, they are not very effective for systemic JIA, indicating a need for more rigorous research to better evaluate their use in these
Objectives: This systematic review assessed the efficacy and safety of abatacept in patients with systemic juvenile idiopathic arthritis (JIA).
Methods: Studies published between 2000 and 2021 were searched using PubMed, Embase, Cochrane, Ichushi-Web, and clinical trial registries. The risk of bias was assessed according to the manual for development clinical practice guidelines by Minds, a project to promote evidence-based medicine in Japan.
Background: Although there are many reports on Juvenile Idiopathic arthritis-associated uveitis (JIA-U) from various countries, especially from Europe and North America, there are few reports from Asia. Our aim was to investigate the epidemiology, characteristics and predictors of JIA-U in Japan.
Methods: Data were retrospectively collected on 726 patients with JIA from medical records as of April 2016 at 15 medical centers specialized in pediatric rheumatic diseases.
We researched the findings of musculoskeletal ultrasound sonography (MSUS) on primary Sjogren's syndrome in childhood (pSS-C) with articular manifestations. The correlation of rheumatoid factor (RF) and anti-cyclic citrullinated peptide antibody (ACPA) were investigated to evaluate the usefulness of MSUS on their articular prognosis. The objective patients are pSS-C cases who visited our hospital complaining joint pain and/or joint swelling and for whom MSUS was performed.
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