Publications by authors named "Kosuke Hideshima"

Already a rare presentation in patients with systemic mastocytosis (SM), chronic diarrhea is even rarer in those with mast cell leukemia (MCL), a subtype of SM. We present a case to illustrate the utility of lower gastrointestinal endoscopy with histological examination in the diagnosis of MCL in a patient with chronic diarrhea. A woman in her 70s presented with persistent diarrhea.

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Abscesses associated with gallbladder perforation are often confined to the peri-gallbladder region. We herein report a rare case of gallbladder perforation in which the abscess cavity extended into the left upper quadrant. A 79-year-old woman developed gallbladder perforation secondary to acalculous cholecystitis.

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IgG4-related disease (IgG4-RD) can cause heterogeneous lesion in various organs. Serum IgG4 levels are useful in monitoring patients with IgG4-RD; however, when it is negative, more careful observation is required. A 58-year-old woman who had been diagnosed with serum IgG4-negative type 1 autoimmune pancreatitis (AIP) 3 years prior visited our hospital for the evaluation of a liver tumor.

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A 57-year-old man visited our hospital for acute cholangitis due to common bile duct (CBD) stones in March 2021. Biliary stenting was performed without any complications. The cholangitis improved rapidly.

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Article Synopsis
  • Gastrointestinal lesions in Behçet's disease (BD) can lead to a rare condition called intestinal BD, which may also be linked to myelodysplastic syndrome (MDS) and certain chromosomal abnormalities, like trisomy 8.
  • A case study details a 58-year-old Japanese woman with intestinal BD who showed persistent symptoms despite treatment and was later diagnosed with low-risk MDS due to abnormal bone marrow findings.
  • The patient ultimately developed pulmonary alveolar proteinosis (PAP), emphasizing the need for doctors to monitor lung issues in patients with intestinal BD and MDS, as genomic abnormalities might influence these complications.
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Sesamum spp. (sesame) are known to accumulate a variety of lignans in a lineage-specific manner. In cultivated sesame (Sesamum indicum), (+)-sesamin, (+)-sesamolin and (+)-sesaminol triglucoside are the three major lignans found richly in the seeds.

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