Publications by authors named "Kosta Panousis"
Article Synopsis
- The study investigates the roles of neutrophil extracellular traps (NETs) and coagulation factor XII (FXII) in the severity of COVID-19, revealing increased FXII expression and activity in COVID-19 lung tissues compared to other conditions.
- It finds that the accumulation of NETs in COVID-19 is partly due to impaired clearance by DNases, which can lead to further FXII activation, contributing to inflammation and coagulopathy.
- The findings suggest that targeting the NET/FXII interaction could be a potential therapeutic approach for managing COVID-19 related complications.
