Publications by authors named "Kossey G"

Article Synopsis
  • The study aims to improve early diagnosis in mothers with complicated medical histories by analyzing the mother-newborn relationship.
  • Two groups of mothers (109 with complicated histories and 31 as a control) were compared, revealing higher rates of chronic fetoplacental insufficiency and preeclampsia in the mothers with complications, alongside more Cesarean deliveries.
  • A negative correlation was found between IL-10 levels in infants and maternal Anti-Toxoplasma-IgG, while Anti-CMV-IgG was linked to increased inflammation in premature infants, indicating potential impacts on neonatal health.
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Objective: Aim: To improve the early diagnosis, course, prediction of the development of Acute Respiratory pathology in children, taking into account the state of antioxidant system (AOS).

Patients And Methods: Materials and Methods: The research group included school-age children (10-14 years old) with Acute Respiratory pathologe (n=111) and a control group (n=25).diseases in comparation.

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Article Synopsis
  • The study aimed to examine respiratory pathology in children aged 10-14, focusing on the inflammatory response and oxidative stress related to acute respiratory infections (ARI).
  • The research involved 111 school-aged children with various upper respiratory conditions, such as acute pharyngitis and bronchitis, and noted correlations between erythrocyte levels and inflammatory markers like IL-1 and TNF-α.
  • Findings indicated that optimized treatment significantly reduced levels of C-reactive protein (CRP) and gamma-interferon (γ-IFN), suggesting a positive impact on inflammatory response and metabolic adaptations in the affected children.
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Objective: The aim: This study aims to investigate and analyze the microbiome of the nasopharyngeal zone in acute respiratory infections (ARI) and their relationship with inflammatory markers.

Patients And Methods: Materials and methods: Examination of 112 children (10-14 years old) with acute respiratory infections (ARI) of the upper respiratory tract was carried out. The control group consisted of 25 healthy children identical in age and examination parameters.

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Patient P., born in 1956, was found by relatives in a state of confused consciousness, an act of involuntary urination and defecation, numbness and weakening of the strength of both lower limbs were recorded. He was taken by ambulance to the reception room of the Regional Clinical Center of Neurosurgery and Neurology.

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Objective: The aim: To investigate the reaction of the bronchi to inhalation of salbutamol in children with different severity of bronchial asthma under the conditions of speleotherapy.

Patients And Methods: Materials and methods: 40 children aged 6-15 years were examined, 20 of them had an intermittent course of the disease, 20 had a mild course, and the children were in the inter-relapse period. Determining the function of external respiration (FER) with a pharmaco-functional test (PFT) with salbutamol was carried out in the dynamics of observation before and after treatment and compared with the indicators of 40 healthy children.

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The article presents clinical observation of a patient with cryptogenic cirrhosis of the liver, a chronic diffuse progressive liver disease, which is manifested by structural rearrange¬ment of its parenchyma. Cryptogenic cirrhosis is cirrhosis of uncertain etiology that lacks definitive clinical and histological criteria for a specific disease. Cryptogenic cirrhosis accounts for nearly 5% to 30% of cases of cirrhosis and nearly 10% of liver transplants.

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Objective: The aim: To investigate the status and possibilities of markers of the inflammatory response of organism in infants with identified IUI born to mothers diagnosed with TORCH infection.

Patients And Methods: Materials and methods: The study group included: infants diagnosed with IUI (n = 40), born to mothers (age 31.31 ± 2.

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The incidence of rare diseases is approximately two cases per 10,000 people. Today, in most cases, orphan diseases are caused by genetic disorders, less often - some forms of oncological, oncohematological, infectious disorders. These conditions have a severe and chronic course, accompanied by a decrease in quality and a reduction in the life expectancy of patients.

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Article Synopsis
  • The study aimed to understand the clinical progression of chronic pancreatitis (CP) in patients who also have hypertension, analyzing 102 cases from a hospital between 2017-2018.
  • Patients typically experienced severe abdominal pain, with different types reported, while 73% also suffered from headaches linked to their hypertension, alongside symptoms like dizziness and shortness of breath.
  • The findings suggest that hypertension negatively affects CP, leading to increased pain severity and other complications for the patients involved in the study.
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The oral-facial-digital syndrome belongs to a group of hereditary diseases, manifested by multiple birth defects (usually, the face and fingers). At the current stage, there are 14 genetic variations of the oral-facial-digital syndrome. The presence of various abnormalities of the oral cavity, face and fingers is common for all of them, but each syndrome has a specific phenotype or type of inheritance.

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