[Parameters of carbohydrate metabolism in the myocardium and the liver during general anesthesia with propofol].

The effect of propofol upon carbohydrate metabolism in rat myocardium is manifested by activated anaerobic glucolysis and glycogenolysis leading to devastation of glycogen. In the liver, the drug leads to activated anaerobic glycolysis and decreases the contribution of pentosophosphate pathways of glucose oxidation to carbohydrate metabolism and produces glycogen-preserving action.

[Application of carbon sorbents in the treatment of experimental peritonitis].

Comparative estimation of efficacy of sorpents SKN-1K, KAU, AU-L in experimental peritonitis was performed. Most favourable effect was observed after performance of hemosorption using AU-L. Sorpent KAU caused very pronounced detoxicational effect, but while its application additional correction of the glucose level is necessary, and that's why it is contraindicated in hypoglycemia.

[Effect of enterosorption effects on hepatic enzyme spectrum in experimental toxic hepatitis].

Influence of a new sorbent based on the AU-L lignin on the hepatic enzyme spectrum has been investigated in rats with experimental toxic hepatitis. The intact animals were in control group. There was a shift in lactate dehydrogenase (LDH) isoenzymic spectrum to the LDH5 side, glucose-6-phosphate dehydrogenase (G-6-PDH) activity increased to 144.

[Activity of the pentosephosphate pathway of glucose metabolism in ischemized skeletal muscles in humans and animals].

Activation of both glucose-6-phosphate dehydrogenase and transketolase was found in skeletal muscles of patients with occlusion impairments of main arteries as well as of animals with acute arterial ischemia.

[Carbohydrate metabolism of the skeletal muscle of the ischemic extremity in acute and chronic occlusion of the major arteries in man].

Activation of glycolysis and glycogenolysis as well as stimulation of the pentosephosphate pathway of glucose oxidation occurred in skeletal muscle of the ischemized legs of patients with occlusive impairments of main arteries.